Theoretical advances and physiological insights from experimental indications of non-classical brain functions

Recent studies suggest that physiological processes in the brain can induce non-classical effects in nuclear spin systems (https://doi.org/10.1088/2399-6528/ac94be), coinciding with blood and cerebrospinal fluid (CSF) pulsations from the heartbeat passing through brain tissue. The brain's nonlinear flow dynamics might, under certain conditions, create analogues of black and white holes, potentially forming wormholes, which could then explain how the brain processes information. This mechanism could also be the basic of the observed non-classicality in the MRI experiment.

We propose a modified Toner-Tu equation, incorporating that flow dynamics are governed by active matter rather than just interacting particles. In accordance with recent findings which have shown that active matter systems can have very low sound speeds, we propose a form of sound with speed matching extracellular transport velocities (https://doi.org/10.1038/s41563-018-0123-4). Then, hypersonic sound waves are created by CSF pulsation entering or leaving the interstitial space via the perivascular system. Those waves vanish upon entering tissue (black hole) and reappear upon exiting (white hole), potentially creating wormholes that exist for several heart cycles. During sleep, this process is replaced by the glymphatic cleaning mechanism, which would explain why the MRI signals disappear then.

Finally, we discuss an analogue AdS/CFT duality which could be the basis of the observed non-classical MRI signal.