Identifying the distribution of nucleoprotein oligomers from mass spectroscopy data.

We compare two codes that use hidden Markov models and nonlinear fitting to determine the distribution of various

oligomers in the polymerization process of macromolecules, specifically nucleoproteins, from mass spectroscopy data. The results

will be compared with stochastic models for polymerization. The goal is to obtain the kinetic rates of the polymerization process.