Physics of the Cell Nucleus

Presentations

• Mechanical Signaling and its Role in Cell Fate and Aging

  ORAL · Invited

  March 20, 2025, 2:30 PM – March 20, 2025, 3:06 PM

  Presenters

  • Adam Engler

    UCSD

  Authors

  • Natalie Kirkland

    UC San Diego

  • Adam Engler

    UCSD

  • Scott H Skalak

    UC San Diego

  View abstract →

• Lamin B Receptor Upregulation in Melanoma Causes Cholesterol-Mediated Nuclear Envelope Fragility During Metastasis

  ORAL

  March 20, 2025, 3:06 PM – March 20, 2025, 3:18 PM

  Publication: Lamin B Receptor Upregulation in Metastatic Melanoma Causes Cholesterol-Mediated Nuclear Envelope Fragility<br>Michelle A. Baird, Robert S. Fischer, Cayla E. Jewett, Daniela Malide, Alexander X. Cartagena-Rivera, Clare M. Waterman<br>bioRxiv 2023.12.21.572889; doi: https://doi.org/10.1101/2023.12.21.572889

  Presenters

  • Michelle Baird

    National Institutes of Health

  Authors

  • Michelle Baird

    National Institutes of Health

  • Cayla Jewett

    Johns Hopkins University School of Medicine

  • Lisa Kratz

    Johns Hopkins University School of Medicine

  • Daniela Malide

    National Institutes of Health

  • Christian Combs

    National Institutes of Health

  • Alexander Cartagena-Rivera,

    National Institutes of Health (NIH)

  • Robert Fischer

    National Institutes of Health

  • Clare Waterman

    National Institutes of Health

  View abstract →

• Chromatin Decompaction-Induced Intranuclear Pressure Drives Nuclear Envelope Rupture During NETosis

  ORAL

  March 20, 2025, 3:18 PM – March 20, 2025, 3:30 PM

  Presenters

  • Hawa R Thiam

    Stanford University

  Authors

  • Minwoo Kang

    Stanford University

  • Hawa R Thiam

    Stanford University

  View abstract →

• Model of T cell migration through the extracellular matrix

  ORAL

  March 20, 2025, 3:30 PM – March 20, 2025, 3:42 PM

  Presenters

  • Sami Alawadhi

    Lehigh University

  Authors

  • Sami Alawadhi

    Lehigh University

  • David M Rutkowski

    Lehigh University

  • Alexander Zhovmer

    FDA

  • Erdem Tabdanov

    Penn State College of Medicine, Department of Pharmacology

  • Dimitrios Vavylonis

    Lehigh University

  View abstract →

• The actin cortex acts as a mechanical memory of morphology in confined migrating cells

  ORAL

  March 20, 2025, 3:42 PM – March 20, 2025, 3:54 PM

  Publication: https://www.biorxiv.org/content/10.1101/2024.08.05.606589v1

  Presenters

  • Sylvain GABRIELE

    University of Mons

  Authors

  • Sylvain GABRIELE

    University of Mons

  View abstract →

• Predicting nuclear shape from cell shape in mammalian cells

  ORAL

  March 20, 2025, 3:54 PM – March 20, 2025, 4:06 PM

  Presenters

  • Ashok Prasad

    Colorado State University

  Authors

  • Ashok Prasad

    Colorado State University

  • Sebastian Lawton

    Department of Chemical and Biological Engineering, Colorado State University

  • Rosaline A Danzman

    Cell and Molecular Biology, Colorado State University

  • Renzo Spagnuolo

    Department of Chemical and Biological Engineering, Colorado State University

  View abstract →

• Vimentin molecular linkages with nesprin-3 enhance nuclear deformation by cell geometric constraints

  ORAL

  March 20, 2025, 4:06 PM – March 20, 2025, 4:18 PM

  Presenters

  • Maxx Swoger

    Department of Physics and BioInspired Institute, Syracuse University

  Authors

  • Maxx Swoger

    Department of Physics and BioInspired Institute, Syracuse University

  • Minh Tri Ho Thanh

    Department of Physics and BioInspired Institute, Syracuse University

  • Fitzroy J Byfield

    Department of Physiology and Institute for Medicine and Engineering, University of Pennslyvania

  • Van B Dam

    Department of Physics and BioInspired Institute, Syracuse University

  • Jessica Williamson

    Department of Biomedical Engineering, Virginia Commonwealth University

  • Bronson Frank

    Department of Biomedical Engineering, The Ohio State University

  • Heidi Hehnly

    Department of Biology and BioInspired Intstitute, Syracuse University, Department of Biology, Syracuse University

  • Daniel Conway

    Department of Bioengineering, The Ohio State University

  • Alison E Patteson

    Syracuse University, Department of Physics and BioInspired Institute, Department of Physics, Syracuse University

  View abstract →

• Abstract Withdrawn

  ORAL Withdrawn

  March 20, 2025, 4:18 PM – March 20, 2025, 4:30 PM

  View abstract →

• Large-scale curvature sensing by epithelial monolayers depends on active cell mechanics and nuclear mechanoadaptation

  ORAL

  March 20, 2025, 4:30 PM – March 20, 2025, 4:42 PM

  Publication: https://www.nature.com/articles/s41567-021-01374-1

  Presenters

  • Marine Luciano

    University of Mons

  Authors

  • Marine Luciano

    University of Mons

  • Sylvain GABRIELE

    University of Mons

  View abstract →

• Microtubule-mediated migration and deformation of a cellular nucleus

  ORAL

  March 20, 2025, 4:42 PM – March 20, 2025, 4:54 PM

  Presenters

  • Yuan-Nan Young

    New Jersey Institute of Technology

  Authors

  • Yuan-Nan Young

    New Jersey Institute of Technology

  • Reza Farhadifar

    Simons Foundation (Flatiron Institute)

  • Libin Lu

    Flatiron Institute

  • Alex Barnett

    Flatiron Institute

  • Michael J Shelley

    Flatiron Institute (Simons Foundation)

  View abstract →

• Chromatin organization modulates cell mechanics​ beyond gene expression

  ORAL

  March 20, 2025, 4:54 PM – March 20, 2025, 5:06 PM

  Presenters

  • Aidan T Cabral

    Stanford University

  Authors

  • Aidan T Cabral

    Stanford University

  • Hawa R Thiam

    Stanford University

  View abstract →

• Mitosis in confining microenvironments

  ORAL

  March 20, 2025, 5:06 PM – March 20, 2025, 5:18 PM

  Presenters

  • Taeyoon Kim

    Purdue University

  Authors

  • Matthew Boyd

    Purdue University

  • Md Foysal Rabbi

    Purdue University

  • Sungmin Nam

    University of Michigan

  • Ovijit Chaudhuri

    Stanford University

  • Taeyoon Kim

    Purdue University

  View abstract →