Cell Fate Transitions I

Presentations

• Timing the decision to override a checkpoint

  ORAL · Invited

  March 19, 2025, 2:30 PM – March 19, 2025, 3:06 PM

  Presenters

  • Sahand J Rahi

    École Polytechnique Fédérale de Lausanne

  Authors

  • Sahand J Rahi

    École Polytechnique Fédérale de Lausanne

  View abstract →

• Shaping fate: geometric methods for cell fate transitions and tissue patterning in stem cells and organoids

  ORAL

  March 19, 2025, 3:06 PM – March 19, 2025, 3:18 PM

  Presenters

  • Dillon Jeffrey Cislo

    Rockefeller University

  Authors

  • Dillon Jeffrey Cislo

    Rockefeller University

  • Eric D Siggia

    Cornell University

  View abstract →

• Integrative Imaging and Machine Learning for Temporal Tracking of Cell Cycle-Resolved Phenotypic Transitions

  ORAL

  March 19, 2025, 3:18 PM – March 19, 2025, 3:30 PM

  Presenters

  • Gaohan Yu

    University of Pittsburgh

  Authors

  • Gaohan Yu

    University of Pittsburgh

  • Jianhua Xing

    University of Pittsburgh

  • Zhiqian Zheng

    University of Pittsburgh

  • Yong Lu

    University of Pittsburgh

  View abstract →

• Abstract Withdrawn

  ORAL Withdrawn

  March 19, 2025, 3:30 PM – March 19, 2025, 3:42 PM

  View abstract →

• Prognostic Value of M1-like and M2-like Tumor-Associated Macrophage Signatures and Their Ratio in Renal Cell Carcinoma

  ORAL

  March 19, 2025, 3:42 PM – March 19, 2025, 3:54 PM

  Presenters

  • Chongming Jiang

    Terasaki Institute for Biomedical Innovation

  Authors

  • Chongming Jiang

    Terasaki Institute for Biomedical Innovation

  • Youngsoo Han

    University of California, Los Angeles

  • Aidan Shen

    Terasaki Institute for Biomedical Innovation

  • Olamide Adefioye

    Terasaki Institute for Biomedical Innovation

  • Yangzhi Zhu

    Terasaki Institute for Biomedical Innovation

  • Xiuying Li

    Terasaki Institute for Biomedical Innovation

  • Zhaohui Wang

    Terasaki Institute for Biomedical Innovation

  View abstract →

• Extracting causal gene perturbations from transcriptomic data

  ORAL

  March 19, 2025, 3:54 PM – March 19, 2025, 4:06 PM

  Presenters

  • Benjamin Kuznets-Speck

    Northwestern University

  Authors

  • Benjamin Kuznets-Speck

    Northwestern University

  • Yogesh Goyal

    Northwestern University

  View abstract →

• Membrane mechanics of exo-endocytosis coupling encodes memory for presynaptic neuron short-term plasticity

  ORAL

  March 19, 2025, 4:06 PM – March 19, 2025, 4:18 PM

  Publication: Ogunmowo T, Jing HY, Raychaudhuri S, Kusick GF, Imoto Y, Li S, Itoh K, Chapman ER, Ha TJ, Watanabe S, Liu J. Membrane compression by synaptic vesicle exocytosis triggers ultrafast endocytosis. Nature Communications 2023, May 20; 14 (1): 2888.

  Presenters

  • Jian Liu

    Johns Hopkins University School of Medicine

  Authors

  • Jian Liu

    Johns Hopkins University School of Medicine

  View abstract →

• Uncovering underlying physical principles and driving forces of cell differentiation and reprogramming from single-cell transcriptomics

  ORAL

  March 19, 2025, 4:18 PM – March 19, 2025, 4:30 PM

  Publication: Ligang Zhu, Songlin Yan, Kun Zhang, Hong Wang, Xiaona Fang* and Jin Wang*, Uncovering underlying physical principles and driving forces of cell differentiation and reprogramming from single-cell transcriptomics, Proc. Natl. Acad. Sci. 121 (34 ) , e2401540121(2024)

  Presenters

  • Jin Wang

    Wenzhou Institute and Stony Brook University, Stony Brook University (SUNY)

  Authors

  • Jin Wang

    Wenzhou Institute and Stony Brook University, Stony Brook University (SUNY)

  View abstract →

• Performing nonlinear stability analysis for a highly interconnected gene network model

  ORAL

  March 19, 2025, 4:30 PM – March 19, 2025, 4:42 PM

  Presenters

  • Nimasha Samarawickrama

    University of North Dakota

  Authors

  • Nimasha Samarawickrama

    University of North Dakota

  • Yen Lee Loh

    University of North Dakota

  • Manu Manu

    University of North Dakota

  • Andrea Repele

    University of North dakota

  • Joanna Handzlik

    University of North Dakota

  View abstract →

• Physical modeling of embryonic transcriptomes identifies collective modes of gene expression

  ORAL

  March 19, 2025, 4:42 PM – March 19, 2025, 4:54 PM

  Publication: https://doi.org/10.1101/2024.07.26.605398

  Presenters

  • Dominic J Skinner

    Flatiron Institute

  Authors

  • Dominic J Skinner

    Flatiron Institute

  • Patrick Lemaire

    Université de Montpellier

  • Madhav Mani

    Northwestern University, Northwestern

  View abstract →

• Finding signatures of low-dimensional geometric landscapes in high-dimensional cell fate transitions

  ORAL

  March 19, 2025, 4:54 PM – March 19, 2025, 5:06 PM

  Publication: Published: scTOP: physics-inspired order parameters for cellular identification and visualization<br>Planned: Finding signatures of low-dimensional geometric landscapes in high-dimensional cell fate transitions

  Presenters

  • Maria Yampolskaya

    Boston University

  Authors

  • Maria Yampolskaya

    Boston University

  • Pankaj Mehta

    Boston University

  View abstract →

• Intrinsic versus extrinsic cellular decision making

  ORAL

  March 19, 2025, 5:06 PM – March 19, 2025, 5:18 PM

  Publication: L. González, B. Han and A. Mugler, Intrinsic versus extrinsic cellular decision making. arXiv preprint arXiv:2410.12081 (2024)

  Presenters

  • Louis Gonzalez

    University of Pittsburgh

  Authors

  • Louis Gonzalez

    University of Pittsburgh

  • Bumsoo Han

    University of Illinois Urbana-Champaign

  • Andrew Mugler

    University of Pittsburgh

  View abstract →

• Differential motility leads to intestinal organoid budding.

  ORAL

  March 19, 2025, 5:18 PM – March 19, 2025, 5:30 PM

  Presenters

  • Sahil Islam

    Indian Institute of Technology, Hyderabad

  Authors

  • Sahil Islam

    Indian Institute of Technology, Hyderabad

  • Suhail Rizvi

    Indian Institute of Technology Hyderabad

  • L Mahadevan

    Harvard University

  • Alberto Elosegui-Artola

    Francis Crick Institute, & King's College London, NW1 1AT, London, UK

  • Anupam Gupta

    Indian Institute of Technology Hyderabad

  View abstract →