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Quantitative and Precision Game Theory Modeling in Hormone Sensitive Cancer

INVITED · MAR-L56 · ID: 2764340

Presentations

  • A History of and Results from Adaptive Cancer Therapy

    ORAL · Invited

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    Publication: Gatenby RA; A change of strategy in the war on cancer. Nature 2009;459(7246):508-9. doi: 10.1038/459508a.<br>Gatenby RA, Artzy-Randrup Y, Epstein T, et al.; Eradicating Metastatic Cancer and the Eco-Evolutionary Dynamics of Anthropocene Extinctions. Cancer Res 2020;80(3):613-623. doi: 10.1158/0008-5472.CAN-19-1941.<br>Stankova K, Brown JS, Dalton WS, et al.; Optimizing Cancer Treatment Using Game Theory: A Review. JAMA Oncol 2019;5(1):96-103. doi: 10.1001/jamaoncol.2018.3395.<br>Gatenby R; Perspective: Finding cancer's first principles. Nature 2012;491(7425):S55. doi: 10.1038/491s55a<br>Gatenby RA, Silva AS, Gillies RJ, et al.; Adaptive therapy. Cancer Res 2009;69(11):4894-903. doi: 10.1158/0008-5472.CAN-08-3658.<br>Zhang J, Cunningham JJ, Brown JS, et al.; Integrating evolutionary dynamics into treatment of metastatic castrate-resistant prostate cancer. Nat Commun 2017;8(1):1816. doi: 10.1038/s41467-017-01968-5.<br>Zhang J C, J, Brown J, Gatenby R; Evolution-based mathematical models significantly prolong response to Abiraterone in metastatic castrate resistant prostate cancer and identify strategies to further improve outcomes Elife 2022. doi: doi: 10.7554/eLife.76284.<br>Mason NT, Burkett JM, Nelson RS, Pow-Sang, JM, Gatenby RA, Kubal T, Peabody JW, Letson GD, McLeod HL, Zhang, J.; Budget Impact of Adaptive Abiraterone Therapy for Castrate-Resistant Prostate Cancer. European Urology 2019<br>Enriquez-Navas PM, Kam Y, Das T, et al.; Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer. Sci Transl Med 2016;8(327):327ra24. doi: 10.1126/scitranslmed.aad7842

    Presenters

    • Robert A Gatenby

      Moffitt Cancer Centre

    Authors

    • Robert A Gatenby

      Moffitt Cancer Centre

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  • Bayesian Control of Metastatic Prostate Cancer

    ORAL · Invited

    –

    Presenters

    • Ioannis G Kevrekidis

      Johns Hopkins University, Department of Chemical and Biomolecular Engineering, John Hopkins University

    Authors

    • Ioannis G Kevrekidis

      Johns Hopkins University, Department of Chemical and Biomolecular Engineering, John Hopkins University

    View abstract →