Biomolecular Condensates II

Presentations

• RNA–RNA interactions encode material properties of biomolecular condensates

  ORAL · Invited

  March 18, 2025, 2:30 PM – March 18, 2025, 3:06 PM

  Publication: Dilimulati Aierken, Vita Zhang, Rachel Sealfon, John C. Marecki, Amy S. Gladfelter, Jerelle A. Joseph*, and Christine A. Roden*. Degree of RNA–RNA complementarity specifies biomolecular condensate morphology (in prep.)

  Presenters

  • Jerelle A Joseph

    Princeton University, Chemical & Biological Engineering Princeton University, Omenn-Darling Bioengineering Institute, Princeton

  Authors

  • Jerelle A Joseph

    Princeton University, Chemical & Biological Engineering Princeton University, Omenn-Darling Bioengineering Institute, Princeton

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• Uncovering material properties of biomolecular condensates via energy landscape framework of stickers and spacers.

  ORAL

  March 18, 2025, 3:06 PM – March 18, 2025, 3:18 PM

  Publication: doi: https://doi.org/10.1101/2024.09.24.614805

  Presenters

  • Subhadip Biswas

    Iowa State University

  Authors

  • Subhadip Biswas

    Iowa State University

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• When B₂ is Not Enough: Unraveling the Limitations of Simple Metrics for Assessing the Phase Behavior of Intrinsically Disordered Proteins

  ORAL

  March 18, 2025, 3:18 PM – March 18, 2025, 3:30 PM

  Presenters

  • Wesley Oliver

    Princeton University

  Authors

  • Wesley Oliver

    Princeton University

  • Michael A. Webb

    Princeton University

  • William M Jacobs

    Princeton University

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• Theory of Dynamics of Intrinsically Disordered Proteins in Biomolecular Condensates

  ORAL

  March 18, 2025, 3:30 PM – March 18, 2025, 3:42 PM

  Presenters

  • Murugappan Muthukumar

    University of Massachusetts Amherst

  Authors

  • Murugappan Muthukumar

    University of Massachusetts Amherst

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• Accurate Modeling of Helical Structures in Disordered Proteins at Residue Resolution: From Single Chains to Condensates

  ORAL

  March 18, 2025, 3:42 PM – March 18, 2025, 3:54 PM

  Presenters

  • Nathaniel Hess

    Chemical & Biological Engineering Princeton University

  Authors

  • Nathaniel Hess

    Chemical & Biological Engineering Princeton University

  • Jerelle A Joseph

    Princeton University, Chemical & Biological Engineering Princeton University, Omenn-Darling Bioengineering Institute, Princeton

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• Abstract Withdrawn

  ORAL Withdrawn

  March 18, 2025, 3:54 PM – March 18, 2025, 4:06 PM

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• A physics-based approach to predict protein phase separation under heat stress

  ORAL

  March 18, 2025, 4:06 PM – March 18, 2025, 4:18 PM

  Presenters

  • Ananya Chakravarti

    Princeton University

  Authors

  • Ananya Chakravarti

    Princeton University

  • Jerelle A Joseph

    Princeton University, Chemical & Biological Engineering Princeton University, Omenn-Darling Bioengineering Institute, Princeton

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• The role of local chain stiffness in modulating viscoelasticity of biomolecular condensates

  ORAL

  March 18, 2025, 4:18 PM – March 18, 2025, 4:30 PM

  Presenters

  • Sean Yang

    Iowa State University

  Authors

  • Sean Yang

    Iowa State University

  • Davit Potoyan

    Iowa State University

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• Nucleation Kinetics determine the Computational Capabilities of Phase-Separation

  ORAL

  March 18, 2025, 4:30 PM – March 18, 2025, 4:42 PM

  Presenters

  • Mason Nesmith Rouches

    University of Chicago

  Authors

  • Mason Nesmith Rouches

    University of Chicago

  • Kristina Trifonova

    University of Chicago

  • Krishna Shrinivas

    Northwestern University

  • Erik Winfree

    California Institute of Technology

  • Arvind Murugan

    University of Chicago

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• Molecular simulations of enzymatic phosphorylation of disordered proteins and their condensates

  ORAL

  March 18, 2025, 4:42 PM – March 18, 2025, 4:54 PM

  Publication: Zippo, E., Dormann, D., Speck, T. & Stelzl, L.L. Molecular simulations of enzymatic phosphorylation of disordered proteins and their condensates, bioRxiv (2024), doi: https://doi.org/10.1101/2024.08.15.607948

  Presenters

  • Emanuele Zippo

    Johannes Gutenberg University Mainz

  Authors

  • Emanuele Zippo

    Johannes Gutenberg University Mainz

  • Dorothee Dormann

    Johannes Gutenberg University Mainz, Institute of Molecular Biology (IMB)

  • Thomas Speck

    University of Stuttgart

  • Lukas Stelzl

    Johannes Gutenberg University Mainz, Institute of Molecular Biology (IMB)

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• Prediction and design of IDR co-phase separation

  ORAL

  March 18, 2025, 4:54 PM – March 18, 2025, 5:06 PM

  Presenters

  • Zhuang Liu

    Princeton University

  Authors

  • Zhuang Liu

    Princeton University

  • William M Jacobs

    Princeton University

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• The Relativity of Simultaneity Is the Link Between the Empirically Demonstrated Association Between Oscillating Electric Fields in the Brain and Cognition: The Pineal Gland of Descartes Does not Work

  ORAL

  March 18, 2025, 5:06 PM – March 18, 2025, 5:18 PM

  Presenters

  • Douglas M Snyder

    None

  Authors

  • Douglas M Snyder

    None

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• Condensate size control in the algal pyrenoid

  ORAL

  March 18, 2025, 5:18 PM – March 18, 2025, 5:30 PM

  Presenters

  • Ned S Wingreen

    Princeton University, Department of Molecular Biology, Princeton University, Princeton NJ 08544, USA

  Authors

  • Ned S Wingreen

    Princeton University, Department of Molecular Biology, Princeton University, Princeton NJ 08544, USA

  • Shan He

    Princeton University

  • Linnea Lemma

    Princeton University

  • Alejandro Martinez-Calvo

    Princeton University

  • Guanhua He

    Stanford University

  • Jessica Hennacy

    Princeton University

  • Lianyong Wang

    Princeton University

  • Sabrina Ergun

    Princeton

  • Martin Jonikas

    Princeton University, Princeton

  • Luke Bunday

    Princeton University

  • Angelo Kayser-Browne

    Princeton University

  • Quan Wang

    NIH

  • Cliff Brangwynne

    Princeton University

  • Martin Jonikas

    Princeton University, Princeton

  View abstract →