Geometry, Mechanics, and Transport in the Cell
ORAL · Invited
Abstract
Cells have their tasks and one is to move or position stuff within (or between) themselves.
Genetic material needs to be properly positioned before a cell division, and development
factors need to land in the right place in a growing egg or embryo. Much of this is accomplished
by the mechanics of the cellular cytoskeleton. Using coarse-grained modeling, abstracted analysis,
and large-scale simulation of fluid-structure interactions integrated with biophysical experiment,
I'll focus on the important role that the geometry of the cell and its evolving contents can play
in the dynamics.
Genetic material needs to be properly positioned before a cell division, and development
factors need to land in the right place in a growing egg or embryo. Much of this is accomplished
by the mechanics of the cellular cytoskeleton. Using coarse-grained modeling, abstracted analysis,
and large-scale simulation of fluid-structure interactions integrated with biophysical experiment,
I'll focus on the important role that the geometry of the cell and its evolving contents can play
in the dynamics.
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Presenters
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Michael J Shelley
Flatiron Institute (Simons Foundation)
Authors
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Michael J Shelley
Flatiron Institute (Simons Foundation)