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Genome Organization and Subnuclear Phenomena II: Active and Passive Processes in Genome Organization

FOCUS · S08 · ID: 1067868

Presentations

  • Transcription is a moving barrier to loop extrusion that shapes the genome

    ORAL

    –

    Publication: Banigan et al., Transcription shapes 3D chromatin organization by interacting with loop extrusion, bioRxiv 475367 (2022)

    Presenters

    • Edward J Banigan

      Massachusetts Institute of Technology, Department of Physics and Institute of Medical Engineering and Science, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139

    Authors

    • Edward J Banigan

      Massachusetts Institute of Technology, Department of Physics and Institute of Medical Engineering and Science, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139

    • Wen Tang

      IMP Vienna

    • Aafke van den Berg

      Massachusetts Institute of Technology

    • Roman Stocsits

      IMP Vienna

    • Gordana Wutz

      IMP Vienna

    • Hugo Brandão

      Massachusetts Institute of Technology

    • Georg Busslinger

      Research Center for Molecular Medicine of the Austrian Academy of Sciences

    • Jan-Michael Peters

      IMP Vienna

    • Leonid A Mirny

      Massachusetts Institute of Technology MIT

    View abstract →

  • Chromatin compartments from correlated active processes

    ORAL

    –

    Presenters

    • Deepti Kannan

      Massachusetts Institute of Technology

    Authors

    • Deepti Kannan

      Massachusetts Institute of Technology

    • Andriy Goychuk

      Massachusetts Institute of Technology

    • Mehran Kardar

      Massachusetts Institute of Technology, Massachusetts Institute of Technology MIT

    • Arup K Chakraborty

      Massachusetts Institute of Technology, MIT

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  • Organizational principles of active chromatin at transcription condensates

    ORAL

    –

    Presenters

    • Jan Spille

      University of Illinois at Chicago, University of Illinois Chicago

    Authors

    • Jan Spille

      University of Illinois at Chicago, University of Illinois Chicago

    • Ganesh Pandey

      University of Illinois at Chicago

    • Alisha Budhathoki

      University of Illinois at Chicago

    • Filmon Medhanie

      University of Illinois at Chicago

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  • Three-dimensional multiphase liquid chromatin model of eukaryotic nucleus

    ORAL

    –

    Publication: [1] A liquid state perspective on dynamics of chromatin compartments, R. Laghmach, M. Di Pierro and D. A. Potoyan, Frontiers in Molecular Biosciences 8 :781981 (2022) https://doi.org/10.3389/fmolb.2021.781981<br>[2] The interplay of chromatin phase separation and lamina interactions in nuclear organization, R. Laghmach, M. Di Pierro and D. A. Potoyan, Biophysical Journal (2021) https://doi.org/10.1016/j.bpj.2021.10.012<br>[3] Mesoscale liquid model of chromatin recapitulates nuclear order of eukaryotes, R. Laghmach, M. Di Pierro and D. A. Potoyan, Biophysical Journal, 0006-3495 (2020) https://doi.org/10.1016/j.bpj.2019.09.013

    Presenters

    • Rabia Laghmach

      Iowa State University

    Authors

    • Rabia Laghmach

      Iowa State University

    • Michele Di Pierro

      Northeastern University

    • Davit Potoyan

      Iowa State University

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  • Condensation dynamics of sticky chromatin

    ORAL

    –

    Publication: Wen Yan, Saad Ansari, Adam Lamson, Matthew A Glaser, Robert Blackwell, Meredith D Betterton, Michael Shelley (2022) Toward the cellular-scale simulation of motor-driven cytoskeletal assemblies eLife 11:e74160<br><br>https://doi.org/10.7554/eLife.74160

    Presenters

    • Adam R Lamson

      Flatiron Institute, Simons Foundation

    Authors

    • Adam R Lamson

      Flatiron Institute, Simons Foundation

    • Olga Troyanskaya

      Lewis-Sigler Institute (Princeton University), Flatiron Institute (SF)

    • Michael J Shelley

      Courant Inst. (NYU), Flatiron Inst. (SF), Flat Iron Institute

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  • Intermolecular interaction and local chromatin density regulate biomolecular condensate growth inside the nucleus

    ORAL

    –

    Presenters

    • Deb S Banerjee

      Carnegie Mellon University

    Authors

    • Deb S Banerjee

      Carnegie Mellon University

    • Tafadzwa Chigumira

      Carnegie Mellon University

    • Josiah Kratz

      Carnegie Mellon University

    • David M Chenoweth

      University of Pennsylvania

    • Shiladitya Banerjee

      Carnegie Mellon University

    • Huaiying Zhang

      Carnegie Mellon University

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  • Multivalent binding proteins can drive collapse and reswelling of chromatin in confinement

    ORAL

    –

    Publication: Multivalent binding proteins can drive collapse and reswelling of chromatin in confinement, S. Guha & M. K. Mitra (Biorxiv link : https://doi.org/10.1101/2022.01.21.477199 )

    Presenters

    • Sougata Guha

      Indian Institute of Technology Bombay

    Authors

    • Sougata Guha

      Indian Institute of Technology Bombay

    • Mithun K Mitra

      Indian Institute of Technology Bombay, Department of Physics, IIT Bombay

    View abstract →