Molecular Machines II
FOCUS · Q08 · ID: 1107048
Presentations
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Millisecond Functional Dynamics of RNA Polymerases Elucidated by Markov State Models
ORAL · Invited
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Publication: 1. Unarta, I.S., Cao, S., Kubo, S., Wang, W., Cheung, P.P.H., Gao, X., Takada, S., Huang, X., "Role of Bacterial RNA Polymerase Gate Opening Dynamics in DNA Loading and Antibiotics Inhibition Elucidated by quasi-Markov State Model", Proc. Nat. Acad. Sci. U.S.A., 118(17), e2024324118, (2021)<br><br>2. Tse K.M., Xu, J., Xu, L., Sheong, F.K., Wang, S., Chow, H.Y., Gao, X., Li, X., Cheung, P.P., Wang, D.*, Zhang, Y., Huang, X., "Intrinsic Cleavage of RNA Polymerase II Adopts a Nucleobase-independent Mechanism Assisted by Transcript Phosphate", Nature Catalysis, 2, 228-235, (2019)<br><br>3. Da, L., Pardo, F. , Xu, L., Silva, D. , Zhang, L. , Gao, X., Wang, D., Huang, X., "Bridge Helix Bending Promotes RNA Polymerase II Backtracking Through a Critical and Conserved Threonine Residue", Nature Communications, 7, 11244, (2016)
Presenters
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Xuhui Huang
University of Wisconsin-Madison
Authors
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Xuhui Huang
University of Wisconsin-Madison
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Speed variations of bacterial replisomes
ORAL
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Publication: Bhat, D., Hauf, S., Plessy, C., Yokobayashi, Y. and Pigolotti, S., 2022. Speed variations of bacterial replisomes. Elife, 11, p.e75884.
Presenters
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Simone Pigolotti
Okinawa Institute of Science & Technolog
Authors
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Simone Pigolotti
Okinawa Institute of Science & Technolog
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Deepak Bhat
Okinawa Institute of Science & Technology
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Samuel Hauf
Okinawa Institute of Science and Technology
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Charles Plessy
Okinawa Institute of Science and Technology
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Yohei Yokobayashi
Okinawa Institute of Science and Technology
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Bacterial replication initiation as precision control in biology
ORAL
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Presenters
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Haochen Fu
UC San Diego
Authors
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Haochen Fu
UC San Diego
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Dongyang Li
University of California, San Diego, Caltech
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Fangzhou Xiao
Caltech
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Suckjoon Jun
University of California, San Diego
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DBIO Thesis Prize Winner: Jonathon L. YulyElectron bifurcation and correlations in biological energy transduction
ORAL · Invited
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Publication: Yuly, J. L., Zhang, P., Lubner, C. E., Peters, J. W., & Beratan, D. N. (2020). Proceedings of the National Academy of Sciences, 117(35), 21045-21051.<br>Yuly, J. L., Zhang, P., Ru, X., Terai, K., Singh, N., & Beratan, D. N. (2021). Chem, 7(7), 1870-1886.<br>Yuly, J.L., Zhang, P., and Beratan, D.N. (2021). Current Opinion in Electrochemistry, 29, 100767.<br>Terai, K., Yuly, J.L., Zhang, P., and Beratan, D.N. (2022). Proceedings of the National Academy of Sciences, Submitted.<br>
Presenters
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Jonathon L Yuly
Princeton University
Authors
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Jonathon L Yuly
Princeton University
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Peng Zhang
Duke University
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Kiriko Terai
Duke University
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David N Beratan
Duke University
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A free-energy profile study of a bipedal single-stranded DNA nanowalker's walking gaits
ORAL
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Presenters
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Too Hon Lin
National University of Singapore
Authors
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Too Hon Lin
National University of Singapore
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How do self-assembled virus-like particles break open to expose their cargo?
ORAL
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Presenters
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Amelia W Paine
Harvard University
Authors
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Amelia W Paine
Harvard University
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Camila Cersosimo
University of Rhode Island
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Vinothan N Manoharan
Harvard University
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Speedy synthetic DNA motors are on a roll
ORAL · Invited
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Publication: "Chemical-to-mechanical molecular computation using DNA-based motors with onboard logic" Selma Piranej, Alisina Bazrafshan & Khalid Salaita; Nature Nanotechnology volume 17, pages514–523 (2022)<br>"Adhesive Dynamics Simulations of Highly Polyvalent DNA Motors" Aaron T. Blanchard, Selma Piranej, Victor Pan, and Khalid Salaita J. Phys. Chem. B 2022, 126, 39, 7495–7509<br>"DNA Gold Nanoparticle Motors Demonstrate Processive Motion with Bursts of Speed Up to 50 nm Per Second"Alisina Bazrafshan, Maria-Eleni Kyriazi, Brandon Alexander Holt, Wenxiao Deng, Selma Piranej, Hanquan Su, Yuesong Hu, Afaf H. El-Sagheer, Tom Brown, Gabriel A. Kwong, Antonios G. Kanaras, and Khalid Salaita, ACS Nano, vol. 15 (5), pg. 8427–8438
Presenters
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Khalid Salaita
Emory University
Authors
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Khalid Salaita
Emory University
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Selma Piranej
Emory University
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Mechanical Properties of BiP (Binding Immunoglobin Protein)
ORAL
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Presenters
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Zahra Alavi
Loyola Marymount University
Authors
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Zahra Alavi
Loyola Marymount University
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