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Molecular Machines II

FOCUS · Q08 · ID: 1107048






Presentations

  • Millisecond Functional Dynamics of RNA Polymerases Elucidated by Markov State Models

    ORAL · Invited

    Publication: 1. Unarta, I.S., Cao, S., Kubo, S., Wang, W., Cheung, P.P.H., Gao, X., Takada, S., Huang, X., "Role of Bacterial RNA Polymerase Gate Opening Dynamics in DNA Loading and Antibiotics Inhibition Elucidated by quasi-Markov State Model", Proc. Nat. Acad. Sci. U.S.A., 118(17), e2024324118, (2021)<br><br>2. Tse K.M., Xu, J., Xu, L., Sheong, F.K., Wang, S., Chow, H.Y., Gao, X., Li, X., Cheung, P.P., Wang, D.*, Zhang, Y., Huang, X., "Intrinsic Cleavage of RNA Polymerase II Adopts a Nucleobase-independent Mechanism Assisted by Transcript Phosphate", Nature Catalysis, 2, 228-235, (2019)<br><br>3. Da, L., Pardo, F. , Xu, L., Silva, D. , Zhang, L. , Gao, X., Wang, D., Huang, X., "Bridge Helix Bending Promotes RNA Polymerase II Backtracking Through a Critical and Conserved Threonine Residue", Nature Communications, 7, 11244, (2016)

    Presenters

    • Xuhui Huang

      University of Wisconsin-Madison

    Authors

    • Xuhui Huang

      University of Wisconsin-Madison

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  • Speed variations of bacterial replisomes

    ORAL

    Publication: Bhat, D., Hauf, S., Plessy, C., Yokobayashi, Y. and Pigolotti, S., 2022. Speed variations of bacterial replisomes. Elife, 11, p.e75884.

    Presenters

    • Simone Pigolotti

      Okinawa Institute of Science & Technolog

    Authors

    • Simone Pigolotti

      Okinawa Institute of Science & Technolog

    • Deepak Bhat

      Okinawa Institute of Science & Technology

    • Samuel Hauf

      Okinawa Institute of Science and Technology

    • Charles Plessy

      Okinawa Institute of Science and Technology

    • Yohei Yokobayashi

      Okinawa Institute of Science and Technology

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  • DBIO Thesis Prize Winner: Jonathon L. YulyElectron bifurcation and correlations in biological energy transduction

    ORAL · Invited

    Publication: Yuly, J. L., Zhang, P., Lubner, C. E., Peters, J. W., & Beratan, D. N. (2020). Proceedings of the National Academy of Sciences, 117(35), 21045-21051.<br>Yuly, J. L., Zhang, P., Ru, X., Terai, K., Singh, N., & Beratan, D. N. (2021). Chem, 7(7), 1870-1886.<br>Yuly, J.L., Zhang, P., and Beratan, D.N. (2021). Current Opinion in Electrochemistry, 29, 100767.<br>Terai, K., Yuly, J.L., Zhang, P., and Beratan, D.N. (2022). Proceedings of the National Academy of Sciences, Submitted.<br>

    Presenters

    • Jonathon L Yuly

      Princeton University

    Authors

    • Jonathon L Yuly

      Princeton University

    • Peng Zhang

      Duke University

    • Kiriko Terai

      Duke University

    • David N Beratan

      Duke University

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  • Speedy synthetic DNA motors are on a roll

    ORAL · Invited

    Publication: "Chemical-to-mechanical molecular computation using DNA-based motors with onboard logic" Selma Piranej, Alisina Bazrafshan & Khalid Salaita; Nature Nanotechnology volume 17, pages514–523 (2022)<br>"Adhesive Dynamics Simulations of Highly Polyvalent DNA Motors" Aaron T. Blanchard, Selma Piranej, Victor Pan, and Khalid Salaita J. Phys. Chem. B 2022, 126, 39, 7495–7509<br>"DNA Gold Nanoparticle Motors Demonstrate Processive Motion with Bursts of Speed Up to 50 nm Per Second"Alisina Bazrafshan, Maria-Eleni Kyriazi, Brandon Alexander Holt, Wenxiao Deng, Selma Piranej, Hanquan Su, Yuesong Hu, Afaf H. El-Sagheer, Tom Brown, Gabriel A. Kwong, Antonios G. Kanaras, and Khalid Salaita, ACS Nano, vol. 15 (5), pg. 8427–8438

    Presenters

    • Khalid Salaita

      Emory University

    Authors

    • Khalid Salaita

      Emory University

    • Selma Piranej

      Emory University

    View abstract →