The nucleoprotein polymerization and nucleation on single-stranded DNA

RAD51 plays a key role in the homologous recombination process. We present a stochastic Monte Carlo lattice model to study how the polymerization of RAD51-RAD51 and the nucleation length distribution of bonded RAD51 on single-stranded and double-stranded DNA evolves over time. We will investigate how targeted RAD51 mutants could perturb the simulation parameters and how it will influence the outcome of the simulation model.