Revisiting assertions of boosted mobility of catalytic enzymes

If it is a truism that science progresses by lively debate, then dueling claims of boosted diffusion (or not) of enzyme diffusion must be leading to rapidly-progressing understanding. In the face of the asserted lack of evidence of boosted diffusion, here we contribute with new experiments: (1) we expand the range of catalytic enzymes for which enhanced diffusion is reported, (2) we visualize the diffusion of fluorescently-labeled single enzymes, and (3) we make progress in explaining large disagreements in the literature about what quantitatively is the turnover rate for particular enzymes.