Hierarchical Models for Omics Data
ORAL · M14 · ID: 1106987
Presentations
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Growing a network via oscillations on nodes
ORAL
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Publication: Diegmiller R, Nunley H, Shvartsman SY, Imran Alsous J. Quantitative models for building and growing fated small cell networks. Interface Focus. 2022 Jun 10;12(4):20210082. doi: 10.1098/rsfs.2021.0082. PMID: 35865502; PMCID: PMC9184967.
Presenters
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Hayden S Nunley
Flatiron Institute (Simons Foundation)
Authors
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Hayden S Nunley
Flatiron Institute (Simons Foundation)
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Matthew Smart
Univ of Toronto
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Stanislav Y Shvartsman
Princeton University
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Mechanisms of mammalian drug resistance acquired during long-term evolution
ORAL
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Publication: planned paper: Mechanisms of mammalian drug resistance acquired during long-term evolution
Presenters
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Yiming Wan
Stony Brook University
Authors
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Yiming Wan
Stony Brook University
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Quanhua Mu
Hong Kong University of Science and Technology
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Rafa? Krzyszto?
Stony Brook University
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Joseph Cohen
Stony Brook University (SUNY)
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Damiano Coraci
Stony Brook University
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Christopher Helenek
Stony Brook University
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Annie Lin
Stony Brook University
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Kevin Farquhar
PONCE Therapeutics
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Jiguang Wang
Hong Kong University of Science and Technology
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Gabor Balazsi
Stony Brook University (SUNY), Laufer Center for Physical and Quantitative Biology, Stony Brook University
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Specificity, cooperativity, synergy, and mechanisms of splice-modifying drugs
ORAL
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Presenters
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Justin B Kinney
Cold Spring Harbor Laboratory
Authors
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Justin B Kinney
Cold Spring Harbor Laboratory
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Experimental quantification of model identifiability and information loss due to distortions in fluorescence microscopy and image processing
ORAL
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Publication: Z. R. Fox and B. Munsky, "The finite state projection based fisher<br>information matrix approach to estimate information and optimize<br>single-cell experiments," PLoS computational biology, vol. 15, no. 1,<br>p. e1006365, 2019.<br><br>H. D. Vo and B. Munsky, "Designing single-cell experiments to harvest<br>fluctuation information while rejecting measurement noise," bioRxiv,<br>pp. 2021–05, 2022.
Presenters
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Michael P May
Colorado State University
Authors
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Michael P May
Colorado State University
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Computational agent-based modelling reveals the role of tumour microenvironment on the success of combination chemotherapy/immunotherapy to treat glioblastoma
ORAL
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Presenters
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Anudeep Surendran
University of Montreal
Authors
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Anudeep Surendran
University of Montreal
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Using the Finite State Projection based Fisher Information Matrix to optimize single-cell experiment designs under different combinations of discrete stochastic models and measurement errors
ORAL
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Publication: Z. R. Fox and B. Munsky, "The finite state projection based fisher<br>information matrix approach to estimate information and optimize<br>single-cell experiments," PLoS computational biology, vol. 15, no. 1,<br>p. e1006365, 2019.<br>Z. R. Fox, G. Neuert, and B. Munsky, "Optimal design of single-cell<br>experiments within temporally fluctuating environments," Complexity,<br>vol. 2020, 2020.<br>H. D. Vo and B. Munsky, "Designing single-cell experiments to harvest<br>fluctuation information while rejecting measurement noise," bioRxiv,<br>pp. 2021–05, 2022.
Presenters
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Joshua Cook
Colorado State University
Authors
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Joshua Cook
Colorado State University
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Live imaging of gut-associated innate immune cell motion
ORAL
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Presenters
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Piyush Amitabh
University of Oregon
Authors
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Piyush Amitabh
University of Oregon
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Jonah Sokoloff
University of Oregon
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Raghuveer Parthasarathy
University of Oregon
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Identifying the transition genes and state specific gene regulation from single-cell transcriptome data with spliceJAC
ORAL
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Publication: -Bocci, Zhou, Nie, "Single-Cell RNA-Seq Analysis Reveals the Acquisition of Cancer Stem Cell Traits and Increase of Cell–Cell Signaling during EMT Progression", (2021) Cancers 13 (22), 5726.<br>-Bocci, Zhou, Nie, "spliceJAC: Transition genes and state specific gene regulation from single-cell transcriptome data", Molecular Systems Biology, In Press.
Presenters
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Federico Bocci
University of California Irvine
Authors
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Federico Bocci
University of California Irvine
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Analytical model for vaccination protocols that optimally produce broadly neutralizing antibodies
ORAL
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Presenters
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Saeed Mahdisoltani
Massachusetts Institute of Technology
Authors
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Saeed Mahdisoltani
Massachusetts Institute of Technology
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Mehran Kardar
Massachusetts Institute of Technology, Massachusetts Institute of Technology MIT
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Arup K Chakraborty
Massachusetts Institute of Technology, MIT
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A model for how T cell-mediated autoimmunity can be triggered by persistent viral infections
ORAL
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Presenters
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Rose Yin
MIT
Authors
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Rose Yin
MIT
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Sam Melton
MIT
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Arup K Chakraborty
Massachusetts Institute of Technology, MIT
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Mehran Kardar
Massachusetts Institute of Technology, Massachusetts Institute of Technology MIT
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Eric Huseby
UMass Chan Medical School
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Optimal design of cocktail boosters to elicit a polyclonal response against related viral strains
ORAL
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Presenters
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Federica Ferretti
MIT
Authors
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Federica Ferretti
MIT
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Arup K Chakraborty
Massachusetts Institute of Technology, MIT
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Mehran Kardar
Massachusetts Institute of Technology, Massachusetts Institute of Technology MIT
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Stochastic modeling for studying the effects of BET inhibitors on the modulation of P-TEFb levels
ORAL
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Presenters
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Miranda D Harkess
University of Massachusetts - Boston
Authors
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Miranda D Harkess
University of Massachusetts - Boston
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Niraj Kumar
University of Massachusetts - Boston
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