Binding and Assembly of Proteins on Membranes

Presentations

• Surface Fluctuating Hydrodynamics Methods for the Drift-Diffusion Dynamics of Proteins and Microstructures within Curved Lipid Bilayer Membranes

  ORAL · Invited

  March 7, 2023, 6:00 PM – March 7, 2023, 6:36 PM

  Publication: Surface Fluctuating Hydrodynamics Methods for the Drift-Diffusion Dynamics of Particles and Microstructures within Curved Fluid Interfaces, D. Rower, M. Padidar, and P. J. Atzberger, Journal of Computational Physics, 455, (2022)<br>https://doi.org/10.1016/j.jcp.2022.110994<br><br>Meshfree Methods on Manifolds for Hydrodynamic Flows on Curved Surfaces: A Generalized Moving Least-Squares (GMLS) Approach, B. J. Gross, N. Trask, P. Kuberry, and P. J. Atzberger, Journal of Computational Physics, Vol. 409, 15 May (2020)<br>https://doi.org/10.1016/j.jcp.2020.109340<br><br>Protein Drift-Diffusion Dynamics and Phase Separation in Curved Cell Membranes and Dendritic Spines: Hybrid Discrete-Continuum Methods, P. Tran, T. Blanpied, P., and P. J. Atzberger, APS Phys. Rev. E, 106, 044402, (2022)<br>https://doi.org/10.1103/PhysRevE.106.044402<br><br>Hydrodynamic Coupling of Particle Inclusions Embedded in Curved Lipid Bilayer Membranes, J.K. Sigurdsson and P.J. Atzberger, 12, 6685-6707, Soft Matter, The Royal Society of Chemistry, (2016)<br>http://dx.doi.org/10.1039/C6SM00194G

  Presenters

  • Paul J Atzberger

    University of California, Santa Barbara

  Authors

  • Paul J Atzberger

    University of California, Santa Barbara

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• Modeling the assembly of curvature inducing proteins in SARS-CoV-2 budding at multiple scales

  ORAL

  March 7, 2023, 6:36 PM – March 7, 2023, 6:48 PM

  Presenters

  • Joseph McTiernan

    University of California, Merced

  Authors

  • Joseph McTiernan

    University of California, Merced

  • Michael Colvin

    University of California, Merced

  • Roya Zandi

    University of California, Riverside

  • Ajay Gopinathan

    University of California, University of California Merced

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• Curvature sensing as an emergent property of multi-scale assembly of septins

  ORAL

  March 7, 2023, 6:48 PM – March 7, 2023, 7:00 PM

  Presenters

  • Wenzheng Shi

    University of North Carolina at Chapel H

  Authors

  • Wenzheng Shi

    University of North Carolina at Chapel H

  • Ehssan Nazockdast

    University of North Carolina at Chapel H

  • Christopher J Edelmaier

    University of North Carolina at Chapel Hill

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• Influence of thermal fluctuations on the association and localization of proteins onto curved membranes

  ORAL

  March 7, 2023, 7:00 PM – March 7, 2023, 7:12 PM

  Publication: "Physical limits to membrane curvature sensing by a single protein" <br>To be submitted to arXiv by the end of October 2022.<br>Authors: Indrajit Badvaram, Brian Camley

  Presenters

  • Indrajit Badvaram

    Johns Hopkins University

  Authors

  • Indrajit Badvaram

    Johns Hopkins University

  • Brian A Camley

    Johns Hopkins University

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• A bifurcation amplifies and integrates a noisy signal from many molecular thermo-receptors

  ORAL

  March 7, 2023, 7:12 PM – March 7, 2023, 7:24 PM

  Presenters

  • Isabella R Graf

    Yale University

  Authors

  • Isabella R Graf

    Yale University

  • Benjamin B Machta

    Physics, Qbio Institute, Yale University, Yale University

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• Probing surface-mediated protein aggregation via FRET-induced lifetime changes

  ORAL

  March 7, 2023, 7:24 PM – March 7, 2023, 7:36 PM

  Presenters

  • Paula-Marie E Ivey

    Purdue University

  Authors

  • Paula-Marie E Ivey

    Purdue University

  • Magaly Guzman Sosa

    Purdue University

  • Arjun Krishnamoorthi

    Texas A&M University

  • Justin A Patel

    Purdue University

  • Jean-Christophe Rochet

    Purdue University

  • Kevin J Webb

    Purdue University

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• The mechanical basis for single amphipathic helix engagement with membranes

  ORAL

  March 7, 2023, 7:36 PM – March 7, 2023, 7:48 PM

  Presenters

  • Christopher J Edelmaier

    University of North Carolina at Chapel Hill

  Authors

  • Christopher J Edelmaier

    University of North Carolina at Chapel Hill

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• All Atom Simulations Reveal Adaptive and Multimodal Membrane Binding of Contractile Ring Anchoring Protein Mid1

  ORAL

  March 7, 2023, 7:48 PM – March 7, 2023, 8:00 PM

  Presenters

  • Aaron R Hall

    Lehigh University

  Authors

  • Aaron R Hall

    Lehigh University

  • Yeol Kyo Choi

    Lehigh University

  • Wonpil Im

    Lehigh University

  • Dimitrios Vavylonis

    Lehigh University

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• Atomic Insights into Amyloid-Induced Membrane Damage

  ORAL

  March 7, 2023, 8:00 PM – March 7, 2023, 8:12 PM

  Publication: Atomic Insights into Amyloid-Induced Membrane Damage. Yanxing Yang, Hannah Distaffen, Sharareh Jalali, Andrew J. Nieuwkoop, Bradley L. Nilsson, and Cristiano L. Dias. ACS Chemical Neuroscience 2022 13 (18), 2766-2777.

  Presenters

  • Yanxing Yang

    Rutgers University

  Authors

  • Yanxing Yang

    Rutgers University

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• Investigation of the synergistic antimicrobial effect of Winter Flounder peptides using molecular dynamics simulations

  ORAL

  March 7, 2023, 8:12 PM – March 7, 2023, 8:24 PM

  Presenters

  • Miruna Serian

    King's College London

  Authors

  • Miruna Serian

    King's College London

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• Exploring Specific and Non-specific Membrane Binding Targets of Self-assembling Human Islet Amyloid Polypeptide Oligomers on Phase-Separated Lipid Domains Using MD Simulations

  ORAL

  March 7, 2023, 8:24 PM – March 7, 2023, 8:36 PM

  Publication: Thuong Pham and Kwan H. Cheng, "Exploring the binding kinetics and behaviors of self-aggregated beta-amyloid oligomers to phase-separated lipid rafts with or without ganglioside-clusters" Biophysical Chemistry, Volume 290, 2022,106874. (ISSN 0301-4622)<br>https://doi.org/10.1016/j.bpc.2022.106874<br>

  Presenters

  • Kwan H Cheng

    Trinity University

  Authors

  • Kwan H Cheng

    Trinity University

  • Angela D Graf

    Trinity University

  • Aakriti Acharya

    Trinity University

  • Thuong L Pham

    Trinity University

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• Antibody binding regulates the dynamics of the membrane-bound prion protein

  ORAL

  March 7, 2023, 8:36 PM – March 7, 2023, 8:48 PM

  Publication: ILIE & Caflisch, BBA-Proteins Proteom. 1870, 140827 (2022)<br>ILIE et al. Biophys. J. 121, 2813 (2022)

  Presenters

  • Ioana M Ilie

    University of Amsterdam

  Authors

  • Ioana M Ilie

    University of Amsterdam

  • Marco Bacci

    University of Zurich

  • Andreas Vitalis

    University of Zurich

  • Amedeo Caflisch

    University of Zurich

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• Force probing ligand-receptor interactions on cells and exosomes

  ORAL

  March 7, 2023, 8:48 PM – March 7, 2023, 9:00 PM

  Presenters

  • sakurako tani

    North Dakota State University

  Authors

  • sakurako tani

    North Dakota State University

  • Lina A Alhalhooly

    North Dakota State University

  • Yongki Choi

    North Dakota State University

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