Cataloguing Actin and Nestin fibers in C17.2 stem cells

An understanding of the cytoskeleton in stem cells is essential for their manipulation. The ability of cells to resist deformation, to transport intercellular cargo and to change shape during movement depends on the cytoskeletal filaments. Additionally, cell culture conditions are important in the proper maintenance of stemness, lineage commitment, and differentiation. This research focuses on the modeling of the cytoskeletal networks such as nestin and actin in C17.2 neural stem cells to create a catalogue of them during differentiation. Initial results will be discussed.