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A Tutorial Model for the Role of Superspreaders in Pandemic Outbreaks

ORAL

Abstract

Popular media have spread widely the concepts behind SIR and related differential-equation models for pandemic spread, and in particular the role of the basic reproduction number R0. However, deterministic models of this sort tend to underestimate the variability of outbreaks, in part because stochastic effects cannot be ignored. Specifically, a huge variability of the infectivity of COVID-infected individuals has been documented, yet the "overdispersion parameter" k quantifying it is hardly ever mentioned even in semipopular accounts. I will give a simple implementation of this idea suitable for an undergraduate-level project. A straightforward Gillespie simulation of the model showcases the dramatic effects of different k values in models with the same R0, and motivates some public-policy conclusions. This material is publicly available as a module that can be introduced into any biological physics course.

Publication: Textbook: Philip Nelson, Physical Models of Living Systems: Probability, Simulation, Dynamics (second edition 2022).

Presenters

  • Phil Nelson

    University of Pennsylvania

Authors

  • Phil Nelson

    University of Pennsylvania