NMR spectroscopy using NV-centers in diamond

Solid-state systems including the nitrogen-vacancy (NV) center in diamond have attracted increasing interest as quantum sensing platforms. Due to their atomic size, NV-centers have allowed for nuclear magnetic resonance (NMR) spectroscopy of nano and micro scale volumes. After recent advances have achieved part per million spectral resolution, they are of particular interest for the analysis of surfaces as well as small biological systems such as single proteins or cells. Furthermore, they allow for electron spin polarization transfer and therefore NMR signal enhancement. While most experiments are done with single NV-centers, we have integrated a dense ensemble of defects within a layer of micron scale thickness with a microfluidic chip. This allows for faster measurement times due to millions of defects being probed simultaneously, as well as fast sample switching and confinement within the micro fluidic channel. We have used this setup for performing NMR microscopy in these channels and performed first steps towards hyperpolarization with NV-centers in diamond.