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Morphogenesis II

ORAL · K05 · ID: 46394

Presentations

  • Global Constraints within the Developmental Program of the Drosophila Wing

    ORAL

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    Publication: Global constraints within the developmental program of the Drosophila wing by Vasyl Alba, James E Carthew, Richard W Carthew, Madhav Mani <br>eLife 2021;10:e66750 DOI: 10.7554/eLife.66750

    Presenters

    • Vasyl Alba

      Northwestern University

    Authors

    • Vasyl Alba

      Northwestern University

    • James E Carthew

      University of Pennsylvania

    • Richard Carthew

      Northwestern University

    • Madhav Mani

      Northwestern University

    View abstract →

  • Mechanical feedback in Drosophila embryonic development

    ORAL

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    Publication: Submitted manuscript: Hannah J. Gustafson, Nikolas Claussen, Stefano De Renzis and Sebastian J. Streichan - "Patterned mechanical feedback establishes a global myosin gradient"

    Presenters

    • Nikolas H Claussen

      University of California, Santa Barbara

    Authors

    • Nikolas H Claussen

      University of California, Santa Barbara

    • Matthew F Lefebvre

      University of California, Santa Barbara

    • Hannah J Gustavson

      University of California, Santa Barbara

    • Noah P Mitchell

      University of California, Santa Barbara

    • Stefano De Renzis

      EMBL Heidelberg

    • Boris I Shraiman

      University of California, Santa Barbara

    • Sebastian J Streichan

      University of California, Santa Barbara, University of California, Santa barbara

    View abstract →

  • Physical mechanisms of tissue compartmentalization andinternalizationin the Drosophila embryo

    ORAL

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    Publication: https://doi.org/10.1016/j.cdev.2021.203721

    Presenters

    • Gonca Erdemci-Tandogan

      University of Toronto, Institute of Biomedical Engineering

    Authors

    • Gonca Erdemci-Tandogan

      University of Toronto, Institute of Biomedical Engineering

    • Jessica C Yu

      University of Toronto, Institute of Biomedical Engineering

    • Negar Balaghi

      University of Toronto, Institute of Biomedical Engineering

    • Veronica Castle

      University of Toronto, Institute of Biomedical Engineering

    • Rodrigo Fernandez-Gonzalez

      University of Toronto, Institute of Biomedical Engineering

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  • In vivo measurements of embryonal tissue mechanics

    ORAL

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    Presenters

    • Behzad Golshaei

      Department of Biomedical Engineering, Duke University, Duke University

    Authors

    • Behzad Golshaei

      Department of Biomedical Engineering, Duke University, Duke University

    • Chonglin Guan

      Physics department, Duke University, Duke University

    • An T Pham

      an.t.pham@duke.edu

    • Janice M Crawford

      Department of Biology, Duke University

    • Daniel P Kiehart

      Department of Biology, Duke University

    • Christoph F Schmidt

      Department of Biomedical Engineering, Duke University; Department of Physics, Duke University; Department of Biology, Duke University, Duke University, Department of Physics and Soft Matter Center, Duke University, Durham, NC 27708, USA

    View abstract →

  • Multi-scale mechanical interactions across layers drive folding morphogenesis in the gut

    ORAL

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    Presenters

    • Noah P Mitchell

      University of California, Santa Barbara

    Authors

    • Noah P Mitchell

      University of California, Santa Barbara

    • Dillon J Cislo

      University of California, Santa Barbara

    • Suraj Shankar

      Harvard University

    • Yuzheng Lin

      University of California, Santa Barbara

    • Boris I Shraiman

      University of California, Santa Barbara

    • Sebastian J Streichan

      University of California, Santa Barbara, University of California, Santa barbara

    View abstract →

  • Electrical cues regulate hydrostatic pressure and swelling in cysts and organoids

    ORAL

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    Publication: Lumenization an epithelium is an essential and ubiquitous step across the morphogenic processes needed to produce hollow structures such as alveoli, kidney ducts, and the gut. Once a lumen is established, it undergoes cycles of swelling and relaxation that precede multiple critical developmental events such as branching. Here, we show that electrical cues can drive the swelling of homotypic epithelial cysts and intestinal organoids. This behavior appears to be driven by electrical modulation of key ion channels responsible for chloride ion transport such as CFTR, which we demonstrate through the use of targeted ion channel inhibitors. Interestingly, the level of swelling varies directly with the strength of the electric field, allowing us to program both the rate of growth and the overall size of a spherical cyst or organoid. The rate of swelling is too rapid to implicate cell proliferation, so we hypothesize hyperelastic deformation of the epithelium. To investigate this, we modify a simple energy-minimization model to consider the effect of stimulation on osmotic pressure, hydrostatic pressure, and ion-mediated pumping to predict accelerated cyst swelling.

    Presenters

    • Isaac B Breinyn

      Princeton University

    Authors

    • Isaac B Breinyn

      Princeton University

    • Gawoon Shim

      Princeton University

    • Daniel J Cohen

      Princeton University

    View abstract →

  • Docking of fire ant rafts using pseudopods

    ORAL

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    Presenters

    • Hungtang Ko

      Georgia Institute of Technology

    Authors

    • Hungtang Ko

      Georgia Institute of Technology

    • Keyana Komilian

      Georgia Institute of Technology

    • Leo Hollingworth

      Georgia Institute of Technology

    • Elliot P Willner

      Georgia Institute of Technology

    • David L Hu

      Georgia Institute of Technology

    View abstract →

  • Machine learning Drosophila embryogenesis

    ORAL

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    Presenters

    • Jonathan Colen

      University of Chicago

    Authors

    • Jonathan Colen

      University of Chicago

    • Noah P Mitchell

      University of California, Santa Barbara

    • Nikolas H Claussen

      University of California, Santa Barbara

    • Marion Raich

      TU Munich

    • Sebastian J Streichan

      University of California, Santa Barbara, University of California, Santa barbara

    • Vincenzo Vitelli

      University of Chicago

    View abstract →

  • Sensing the fly embryo's transcription factors

    ORAL

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    Presenters

    • Marianne Bauer

      Princeton University

    Authors

    • Marianne Bauer

      Princeton University

    • Mariela D Petkova

      Harvard University

    • Thomas Gregor

      Princeton University, Department of Physics Princeton University, Princeton University, Princeton, NJ, USA and Institut Pasteur, Paris, France

    • Eric F Wieschaus

      Department of Molecular Biology Princeton University, Princeton University

    • William S Bialek

      Princeton University

    View abstract →

  • A spontaneous strain mediated mechanical model of the Drosophila wing disc eversion

    ORAL

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    Presenters

    • Abhijeet Krishna

      Max Planck Institute of Molecular Cell Biology and Genetics

    Authors

    • Abhijeet Krishna

      Max Planck Institute of Molecular Cell Biology and Genetics

    • Jana Fuhrmann

      Max Planck Institute of Molecular Cell Biology and Genetics

    • Charlie Duclut

      Max Planck Institute for the Physics of Complex Systems, Dresden, Germany, Max Planck Institute of Physics of Complex Systems, Max Planck Institute for the Physics of Complex Systems

    • Frank Jülicher

      Max Planck Institut for the Physics of Complex Systems, Dresden, Max Planck Institute for the Physics of Complex Systems, Max Planck Institute of Physics of Complex Systems

    • Natalie Dye

      Physics of Life, TU Dresden

    • Carl D Modes

      Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany, Max Planck Institute of Molecular Cell Biology and Genetics, MPI-CBG, MPI-PKS, CSBD, Max Planck Institut for Molecular Cell Biology and Genetics (MPI-CBG), 01307 Dresden, Germany., Max Planck Institute for Molecular Cell Biology and Genetics

    View abstract →

  • Cellular Compartmentalisation and Receptor Promiscuity as a strategy for accuracy and robustness in Positional Inference during Morphogenesis

    ORAL

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    Publication: KS Iyer, C Prabhakara, S Mayor, M Rao. Cellular Compartmentalisation and Receptor Promiscuity as a strategy for accuracy and robustness in Positional Inference during Morphogenesis (in preparation)

    Presenters

    • Krishnan S Iyer

      Tata Institute of Fundamental Research (, Simons Center for the Study of Living Machines, National Center for Biological Sciences - TIFR

    Authors

    • Krishnan S Iyer

      Tata Institute of Fundamental Research (, Simons Center for the Study of Living Machines, National Center for Biological Sciences - TIFR

    • Chaitra Prabhakara

      National Center for Biological Sciences - TIFR

    • Madan Rao

      Simons Centre for the Study of Living Machines, National Centre for Biological Sciences (TIFR), Bangalore 560065, India, National Center For Biological Sciences, Bengaluru, Simons Center for the Study of Living Machines, National Center for Biological Sciences - TIFR

    • Satyajit Mayor

      National Center for Biological Sciences - TIFR

    View abstract →

  • Modeling helical shape formation in bacteria

    ORAL

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    Presenters

    • Luyi Qiu

      Harvard University

    Authors

    • Luyi Qiu

      Harvard University

    • Cesar L Pastrana

      Technical University of Munich

    • Ulrich Gerland

      Technical University of Munich

    • Shahaf Armon

      Weizmann Institute of Science

    • Ariel Amir

      Harvard University

    View abstract →