Analysis of the Length Distribution of Microtubules with Different Structural Compositions

Microtubules are one of the cellular filaments that are structured from alpha tubulin and beta tubulin. These biofilaments are dynamic and randomly switch between growing and shrinking phases while they polymerize. The four major parameters that define the polymerization specifications of microtubules are growing velocity, shrinking velocity, frequency of catastrophe, and frequency of rescue. Experimental evidence and theoretical analysis indicate that the length distribution of microtubules depends on these polymerization parameters. In this study, we will analyze the length distribution of different types of microtubules that have structurally distinct compositions from one another. Both the theoretical and experimental results will be compared and analyzed.