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Intracellular Transport I: Motor-driven Transport and Cytoskeletal Activity

FOCUS · D07 · ID: 46299

Presentations

  • Mechanics of Cytoplasmic Dynein

    ORAL · Invited

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    Publication: 1. Sinan Can, Samuel Lacey, Mert Gur, Andrew P. Carter, Ahmet Yildiz. Dynein's directionality is controlled by the angle and length of its stalk. Nature 566(7744):407-410 (2019).<br>2. Mohamed M. Elshenawy, John T. Canty, Liya Oster, Luke S. Ferro, Zhou Zhou, Scott C. Blanchard, Ahmet Yildiz. Cargo adaptors regulate stepping and force generation of mammalian dynein-dynactin. Nature Chemical Biology 2019; 15, 1093–1101.<br>3. Yasin Ezber, Vladislav Belyy, Sinan Can, Ahmet Yildiz. Dynein Harnesses Active Fluctuations of Microtubules for Faster Movement. Nature Physics 16, 312–316 (2020).<br>4. Mohamed M. Elshenawy, Emre Kusakci, Sara Volz, Janina Baumbach, Simon L. Bullock, Ahmet Yildiz. Lis1 activates dynein motility by modulating its pairing with dynactin. Nature Cell Biology 22(5):570-578 (2020).<br>5. Luke S Ferro, Lisa Eshun-Wilson, Jonathan Fernandes, Qianglin Fang, Eva Nogales, Ahmet Yildiz. The mechanism of motor inhibition by microtubule-associated proteins. biorXiv doi: 10.1101/2020.10.22.351346 (under review in Science).

    Presenters

    • Ahmet Yildiz

      University of California, Berkeley

    Authors

    • Ahmet Yildiz

      University of California, Berkeley

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  • Spiraling galaxies of microtubules

    ORAL

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    Presenters

    • Michael J Shelley

      Courant Inst. (NYU), Flatiron Inst. (SF), Flatiron Institute and New York University, Flatiron Institute and Courant Institute, New York University, Flatiron Institute

    Authors

    • Michael J Shelley

      Courant Inst. (NYU), Flatiron Inst. (SF), Flatiron Institute and New York University, Flatiron Institute and Courant Institute, New York University, Flatiron Institute

    • Jesse Gatlin

      Department of Molecular Biology, University of Wyoming

    • Gokberk Kabacaoglu

      Simons Foundation, Center for Computational Biology, Flatiron Institute, & Bilkent University, Turkey

    • ABDULLAH BASHAR SAMI

      Department of Molecular Biology, University of Wyoming

    • David Stein

      Flatiron Institute

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  • aLENS: towards the cellular-scale simulation of motor-driven cytoskeletal assemblies

    ORAL

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    Presenters

    • Wen Yan

      Simons Foundation

    Authors

    • Wen Yan

      Simons Foundation

    • Saad Ansari

      University of Colorado, Boulder

    • Adam R Lamson

      Simons Foundation

    • Matt Glaser

      University of Colorado, Boulder

    • Meredith D Betterton

      University of Colorado, Boulder

    • Michael J Shelley

      Courant Inst. (NYU), Flatiron Inst. (SF), Flatiron Institute and New York University, Flatiron Institute and Courant Institute, New York University, Flatiron Institute

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  • Modeling the collective motion of microtubules driven by mobile kinesin motors

    ORAL

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    Presenters

    • Madhuvanthi Athani

      University of California, Merced, Department of Physics, University of California, Merced and Department of Physics and Astronomy, Johns Hopkins University

    Authors

    • Madhuvanthi Athani

      University of California, Merced, Department of Physics, University of California, Merced and Department of Physics and Astronomy, Johns Hopkins University

    • Fabian Jan Schwarzendahl

      Heinrich-Heine-Universität Düsseldorf

    • Fereshteh L Memarian

      University of California, Merced

    • Ajay Gopinathan

      University of California, Merced, University of California Merced

    • Linda S Hirst

      University of California, Merced, University of California Merced

    • Kinjal Dasbiswas

      University of California, Merced, Merced

    • Daniel A Beller

      University of California, Merced, Department of Physics, University of California, Merced; Department of Physics and Astronomy, Johns Hopkins University, Johns Hopkins University, University of California, Merced, and Department of Physics and Astronomy, Johns Hopkins University, Department of Physics, University of California, Merced and Department of Physics and Astronomy, Johns Hopkins University

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  • Self-organization of microtubules and motors drive large-scale intracellular flows in cells

    ORAL

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    Presenters

    • Reza Farhadifar

      Simons Foundation

    Authors

    • Reza Farhadifar

      Simons Foundation

    • Sayantan Dutta

      Princeton University

    • Gokberk Kabacaoglu

      Simons Foundation, Center for Computational Biology, Flatiron Institute, & Bilkent University, Turkey

    • Wen Lu

      Northwestern University

    • Vladimir I Gelfand

      Northwestern University

    • Stanislav Y Shvartsman

      Princeton University, Princeton University, Simons Foundation

    • Michael J Shelley

      Courant Inst. (NYU), Flatiron Inst. (SF), Flatiron Institute and New York University, Flatiron Institute and Courant Institute, New York University, Flatiron Institute

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  • Steady-state directional flow in active model cytoskeletal network

    ORAL

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    Presenters

    • Jianguo Zhao

      Max Planck Institute for the Physics of Complex Systems

    Authors

    • Jianguo Zhao

      Max Planck Institute for the Physics of Complex Systems

    • Charlie Duclut

      Max Planck Institute for the Physics of Complex Systems, Dresden, Germany, Max Planck Institute of Physics of Complex Systems, Max Planck Institute for the Physics of Complex Systems

    • Rahil Golipour

      University of Ottawa

    • An Pham

      Duke University

    • Behzad Golshaei

      Department of Biomedical Engineering, Duke University, Duke University

    • Chonglin Guan

      Physics department, Duke University, Duke University

    • Mingru Li

      Duke University

    • Rudolf Oldenbourg

      Marine Bio Lab

    • James L Harden

      Univ of Ottawa

    • Frank Jülicher

      Max Planck Institut for the Physics of Complex Systems, Dresden, Max Planck Institute for the Physics of Complex Systems, Max Planck Institute of Physics of Complex Systems

    • Christoph F Schmidt

      Department of Biomedical Engineering, Duke University; Department of Physics, Duke University; Department of Biology, Duke University, Duke University, Department of Physics and Soft Matter Center, Duke University, Durham, NC 27708, USA

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