Synthetic Biology I

Presentations

• Molecular Implementations of Positive and Negative Feedback Inform Robustness in Biological Oscillator Motifs

  ORAL

  March 14, 2022, 9:00 AM – March 14, 2022, 9:12 AM

  Publication: Molecular Implementations of Positive and Negative Feedback Inform Robustness in Biological Oscillator Motifs

  Presenters

  • Chaitra Agrahar

    University of Illinois at Chicago

  Authors

  • Chaitra Agrahar

    University of Illinois at Chicago

  • Michael J Rust

    University of Chicago, Department of Molecular Genetics and Cell Biology, University of Chicago

  View abstract →

• Metabolic Pathway Design Using Active Subspaces

  ORAL

  March 14, 2022, 9:12 AM – March 14, 2022, 9:24 AM

  Presenters

  • Andre Archer

    Northwestern University

  Authors

  • Andre Archer

    Northwestern University

  • Taylor Nichols

    Northwestern University

  • Niall Mangan

    Northwestern University

  • Danielle Tullman-Ercek

    Northwestern University

  View abstract →

• Building synthetic circuits to achieve cascading cell fate transitions

  ORAL · Invited

  March 14, 2022, 9:24 AM – March 14, 2022, 10:00 AM

  Publication: Zhang, R., Goetz, H, Melendez-Alvarez, J., Li, J., Ding, T., Wang, X., and Tian, X.-J., Winner-Takes-All Resource Competition Redirects Cascading Cell Fate Transitions. Nature Communications.12, 853, 2021.

  Presenters

  • Xiaojun Tian

    Arizona State University

  Authors

  • Xiaojun Tian

    Arizona State University

  • Rong Zhang

    Arizona State University

  • Hanah Goetz

    Arizona State University

  • Juan Melendez-Alvarez

    Arizona State University

  • Jiao Li

    Arizona State University

  • Tian Ding

    Zhejiang University

  • Xiao Wang

    Arizona State University

  View abstract →

• Identifying Mechanisms of Gene Circuit Evolution that Elicit Mammalian Drug Resistance

  ORAL

  March 14, 2022, 10:00 AM – March 14, 2022, 10:12 AM

  Publication: Farquhar, K. S., Charlebois, D. A., Szenk, M., Cohen, J., Nevozhay, D., & Balázsi, G. (2019). Role of network-mediated stochasticity in mammalian drug resistance. Nature communications, 10(1), 1-14.

  Presenters

  • Joseph Cohen

    Stony Brook University (SUNY)

  Authors

  • Joseph Cohen

    Stony Brook University (SUNY)

  • Quanhua Mu, Ph.D

    Hong Kong University of Science and Technology

  • Yiming Wan

    Stony Brook University (SUNY), Stony Brook University (SUNY), Biomedical Engineering Department and Laufer Center for Physical and Quantitative Biology

  • Kevin Farquar, Ph.D

    Independent Researcher

  • Gábor Balázsi

    State Univ of NY - Stony Brook, Stony Brook University (SUNY), Stony Brook University (SUNY), Biomedical Engineering Department and Laufer Center for Physical and Quantitative Biology, Stony Brook University

  View abstract →

• The Role of Energy Dissipation in Shaping Eukaryotic Transcriptional Regulation

  ORAL

  March 14, 2022, 10:12 AM – March 14, 2022, 10:24 AM

  Presenters

  • Zheng Diao

    Rice Univ

  Authors

  • Zheng Diao

    Rice Univ

  • Caleb J Bashor

    Rice Univ

  • Oleg A Igoshin

    Rice Univ

  View abstract →

• Advancing the frontiers of design-driven medicine: engineering programmable cell-based therapies and diagnostics

  ORAL · Invited

  March 14, 2022, 10:24 AM – March 14, 2022, 11:00 AM

  Publication: Muldoon, J. J., Kandula, V., Hong, M., Donahue, P. S., Boucher, J. D., Bagheri, N., & Leonard, J. N. (2021). Model-guided design of mammalian genetic programs. Science Advances, 7(8), eabe9375. https://doi.org/10.1126/sciadv.abe9375

  Presenters

  • Joshua N Leonard

    Northwestern University

  Authors

  • Joshua N Leonard

    Northwestern University

  View abstract →

• Dynamics of DNA methylation and persistence of epigenetic memory

  ORAL

  March 14, 2022, 11:00 AM – March 14, 2022, 11:12 AM

  Presenters

  • Sagnik Ghosh

    Brandeis University

  Authors

  • Sagnik Ghosh

    Brandeis University

  • Arnab Datta

    Brandeis University

  • Colin Kunze

    Boston University

  • Jane Kondev

    Brandeis University, Brandeis Univ

  • Ahmad S Khalil

    Boston University

  View abstract →

• Deciphering the influence of genome architecture in a minimized bacterial genome

  ORAL

  March 14, 2022, 11:12 AM – March 14, 2022, 11:24 AM

  Presenters

  • Troy A Brier

    Univeristy of Illinois at Urbana-Champaign, University of Illinois at Urbana-Champaign Department of Chemistry

  Authors

  • Troy A Brier

    Univeristy of Illinois at Urbana-Champaign, University of Illinois at Urbana-Champaign Department of Chemistry

  • Pratap Venepally

    J. Craig Venter Institute

  • John I Glass

    J. Craig Venter Institute

  • Zaida (Zan) Luthey-Schulten

    University of Illinois at Urbana-Champaign, University of Illinois Urbana-Champaign, University of Illinois at Urbana-Champaign Department of Chemistry

  View abstract →

• A novel riboswitch design for integrative, functional RNA detection in mammalian cells.

  ORAL

  March 14, 2022, 11:24 AM – March 14, 2022, 11:36 AM

  Presenters

  • Rafał Krzysztoń

    Stony Brook University, Stony Brook University (SUNY), Biomedical Engineering Department and Laufer Center for Physical and Quantitative Biology

  Authors

  • Rafał Krzysztoń

    Stony Brook University, Stony Brook University (SUNY), Biomedical Engineering Department and Laufer Center for Physical and Quantitative Biology

  • Yiming Wan

    Stony Brook University (SUNY), Stony Brook University (SUNY), Biomedical Engineering Department and Laufer Center for Physical and Quantitative Biology

  • Julia Petreczky

    Stony Brook University (SUNY), Biomedical Engineering Department and Laufer Center for Physical and Quantitative Biology

  • Gábor Balázsi

    State Univ of NY - Stony Brook, Stony Brook University (SUNY), Stony Brook University (SUNY), Biomedical Engineering Department and Laufer Center for Physical and Quantitative Biology, Stony Brook University

  View abstract →

• The state of water in lipidic mesophase

  ORAL

  March 14, 2022, 11:36 AM – March 14, 2022, 11:48 AM

  Publication: 1. Yao, Y.; Zhou, T.; Färber, R.; Grossner, U.; Floudas, G.; Mezzenga, R. Designing cryo-enzymatic reactions in subzero liquid water by lipidic mesophase nanoconfinement. Nature Nanotechnology, 2021, 16, 802-810. DOI: 10.1038/s41565-021-00893-5.<br>2. Yao, Y., Catalini, S., Kutus, B., Hunger, J., Foggi, P., Mezzenga, R., Probing water state during lipidic mesophases phase transitions, Angewandte Chemie, 2021, in press. DOI: org/10.1002/anie.202110975.

  Presenters

  • Yang Yao

    Lab of food and soft materials, D-HEST, ETH Zurich, Switzerland

  Authors

  • Yang Yao

    Lab of food and soft materials, D-HEST, ETH Zurich, Switzerland

  • Sara Catalini

    LENS, Italy

  • Bence Kutus

    Max Planck Institute for Polymer Research, Mainz, Germany

  • Johannes Hunger

    Max Planck Institute for Polymer Research, Mainz, Germany

  • Tao Zhou

    Lab of food and soft materials, D-HEST, ETH Zurich

  • Paolo Foggi

    LENS, Italy

  • George Floudas

    Univ of Ioannina

  • Raffaele Mezzenga

    ETH Zurich

  View abstract →