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Theory of microphase separation and micellization in solutions of intrinsically disordered proteins

ORAL

Abstract

We have formulated a theory of micellization and microphase separation in aqueous solutions of intrinsically disordered proteins, using self-consistent field theory and scaling arguments. The size and shape of micelles and critical micelle concentration will be presented for dilute solutions. For the case of microphase separation at higher protein concentrations, order-disorder transition, order-order transitions, and the dependence of domain sizes on protein sequence will be presented.

Presenters

  • Siao-Fong Li

    University of Massachusetts Amherst

Authors

  • Siao-Fong Li

    University of Massachusetts Amherst

  • Murugappan Muthukumar

    University of Massachusetts Amherst, Polymer science and engineering, University of Massachusetts Amherst