Effects of External Electric Field on the Thermodynamic Properties of Microtubules During Dynamic Instability

Abstract We investigate the dynamics of microtubules (MTs) under the influence of the electric field using the Ising model. The mean-field theory is used to compute the thermodynamic properties of the model such as polarization, critical temperature, and free energy in the absence and presence of the external electric field. The results show that the magnitude of the external electric field plays a critical role in symmetry breaking in MTs. However, when the magnitude of the external electric field is weak and the environmental temperature is below the critical value, the system adopts a favorable configuration where the transmission process occurs.