Macromolecular Phase Separation in Biology I

Presentations

• Protein condensates as aging Maxwell fluids

  Invited

  March 5, 2020, 1:15 PM – March 5, 2020, 1:51 PM

  Presenters

  • Louise Jawerth

    Max Planck Institute for the Physics of Complex Systems, for the Physics of Complex Systems, Max Planck Institute

  Authors

  • Louise Jawerth

    Max Planck Institute for the Physics of Complex Systems, for the Physics of Complex Systems, Max Planck Institute

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• Surface Fluctuations and Coalescence of Nucleolar Droplets in the Human Cell Nucleus

  ORAL

  March 5, 2020, 1:51 PM – March 5, 2020, 2:03 PM

  Presenters

  • Christina M. Caragine

    Physics, New York Univ NYU

  Authors

  • Christina M. Caragine

    Physics, New York Univ NYU

  • Shannon C Haley

    Physics, New York Univ NYU, University of California, Berkeley

  • Alexandra Zidovska

    Physics, New York Univ NYU, New York Univ NYU

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• Phase separation in the nucleus is limited by chromatin mechanics

  ORAL

  March 5, 2020, 2:03 PM – March 5, 2020, 2:15 PM

  Presenters

  • Yaojun Zhang

    Princeton University

  Authors

  • Yaojun Zhang

    Princeton University

  • Daniel Lee

    Princeton University

  • Yigal Meir

    Ben-Gurion University, Physics, Ben-Gurion University

  • Cliff Brangwynne

    Princeton University, Department of Chemical and Biological Engineering, Princeton University; Howard Hughes Medical Institute

  • Ned Wingreen

    Princeton University, Department of Molecular Biology; Lewis-Sigler Institute for Integrative Genomics, Princeton University

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• Subdiffusive Dynamics of Optogenetic Droplets Report on Local Chromatin Mechanics

  ORAL

  March 5, 2020, 2:15 PM – March 5, 2020, 2:27 PM

  Presenters

  • Daniel Lee

    Lewis-Sigler Institute for Integrative Genomics, Princeton University

  Authors

  • Daniel Lee

    Lewis-Sigler Institute for Integrative Genomics, Princeton University

  • Shunsuke Shimobayashi

    Department of Chemical and Biological Engineering, Princeton University

  • Yi-Che Chang

    Department of Chemical and Biological Engineering, Princeton University

  • Amy R Strom

    Department of Chemical and Biological Engineering, Princeton University

  • Ned Wingreen

    Princeton University, Department of Molecular Biology; Lewis-Sigler Institute for Integrative Genomics, Princeton University

  • Cliff Brangwynne

    Princeton University, Department of Chemical and Biological Engineering, Princeton University; Howard Hughes Medical Institute

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• Converting Stochastic Assembly into an Assembly Line: Non-Equilibrium Droplet Dynamics Assists Ribosome Formation

  ORAL

  March 5, 2020, 2:27 PM – March 5, 2020, 2:39 PM

  Presenters

  • Tyler Harmon

    Max Planck Institute for the Physics of Complex Systems

  Authors

  • Tyler Harmon

    Max Planck Institute for the Physics of Complex Systems

  • Frank Julicher

    Max-Planck-Institute for the Physics of Complex Systems, Max Planck Institute for the Physics of Complex Systems, Max Planck Institute for the Physics of Complex Systems, Dresden, Germany

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• Reentrant Liquid Condensation of Ribonucleoprotein–RNA Complexes

  ORAL

  March 5, 2020, 2:39 PM – March 5, 2020, 2:51 PM

  Presenters

  • Muralikrishna Raju

    Iowa State University

  Authors

  • Muralikrishna Raju

    Iowa State University

  • Rabia Laghmach

    Iowa State University

  • Davit Potoyan

    Iowa State University

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• Size selection of phase-separated liquid droplets in strain-stiffening elastic networks

  ORAL

  March 5, 2020, 2:51 PM – March 5, 2020, 3:03 PM

  Presenters

  • Sheng Mao

    Princeton University

  Authors

  • Sheng Mao

    Princeton University

  • Mikko Haataja

    Princeton University

  • Andrej Kosmrlj

    Princeton University

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• A hydrodynamic instability drives TPX2 protein droplet formation on microtubules and leads to branching microtubule nucleation

  ORAL

  March 5, 2020, 3:03 PM – March 5, 2020, 3:15 PM

  Presenters

  • Sagar Setru

    Princeton University

  Authors

  • Sagar Setru

    Princeton University

  • Bernardo Gouveia

    Princeton University

  • Raymundo Alfaro-Aco

    Princeton University

  • Matthew R King

    Princeton University

  • Howard A Stone

    Princeton University, Department of Mechanical and Aerospace Engineering, Princeton University

  • Joshua Shaevitz

    Princeton University, Physics and the Lewis-Sigler Institute, Princeton University, Physics, Princeton University

  • Sabine Petry

    Princeton University

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• Motif Sequences and Intracellular Phase Separation

  ORAL

  March 5, 2020, 3:15 PM – March 5, 2020, 3:27 PM

  Presenters

  • Benjamin Weiner

    Princeton University

  Authors

  • Benjamin Weiner

    Princeton University

  • Yigal Meir

    Ben-Gurion University, Physics, Ben-Gurion University

  • Ned Wingreen

    Princeton University, Department of Molecular Biology; Lewis-Sigler Institute for Integrative Genomics, Princeton University

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• Coupling signaling cascades to membrane criticality

  ORAL

  March 5, 2020, 3:27 PM – March 5, 2020, 3:39 PM

  Presenters

  • Taylor Schaffner

    Yale University

  Authors

  • Taylor Schaffner

    Yale University

  • Benjamin B Machta

    Physics, Yale University, Yale University, Department of Physics, Yale University

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• Wetting of Critical Membranes by Protein Droplets

  ORAL

  March 5, 2020, 3:39 PM – March 5, 2020, 3:51 PM

  Presenters

  • Mason Rouches

    Molecular Biophysics and Biochemistry, Yale University

  Authors

  • Mason Rouches

    Molecular Biophysics and Biochemistry, Yale University

  • Sarah Veatch

    Biophysics, University of Michigan

  • Benjamin B Machta

    Physics, Yale University, Yale University, Department of Physics, Yale University

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• Probing the Dynamics of Optically Induced Protein Droplets with Single-Walled Carbon Nanotubes

  ORAL

  March 5, 2020, 3:51 PM – March 5, 2020, 4:03 PM

  Presenters

  • Hugh Higinbotham

    Massachusetts Institute of Technology MIT

  Authors

  • Hugh Higinbotham

    Massachusetts Institute of Technology MIT

  • Sebastian Coupe

    Massachusetts Institute of Technology MIT

  • Yoon Jung

    Massachusetts Institute of Technology MIT

  • Nikta Fakhri

    Massachusetts Institute of Technology MIT, MIT, Physics, Massachusetts Institute of Technology, Massachusetts Institute of Technology

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• Measuring protein concentrations in biomolecular condensates via quantitative phase microscopy

  ORAL

  March 5, 2020, 4:03 PM – March 5, 2020, 4:15 PM

  Presenters

  • Patrick McCall

    Max Planck Institute for the Physics of Complex Systems, Max Planck Institute of Molecular Cell Biology and Genetics; Max Planck Institute for the Physics of Complex Systems; Center for Systems Biology Dresden

  Authors

  • Patrick McCall

    Max Planck Institute for the Physics of Complex Systems, Max Planck Institute of Molecular Cell Biology and Genetics; Max Planck Institute for the Physics of Complex Systems; Center for Systems Biology Dresden

  • Kyoohyun Kim

    Biotechnology Center, Technische Universität Dresden; Max Planck Institute for the Science of Light

  • Jie Wang

    Max Planck Institute of Molecular Cell Biology and Genetics

  • Anatol W. Fritsch

    Max Planck Institute of Molecular Cell Biology and Genetics; Max Planck Institute for the Physics of Complex Systems; Center for Systems Biology Dresden

  • Andrey Poznyakovskiy

    Max Planck Institute of Molecular Cell Biology and Genetics

  • Benedict Diederich

    Leibniz Institute of Photonic Technology

  • Moritz Kreysing

    Max Planck Institute of Molecular Cell Biology and Genetics; Center for Systems Biology Dresden

  • Rainer Heintzmann

    Leibniz Institute of Photonic Technology; Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich-Schiller-University Jena

  • Jochen Guck

    Biotechnology Center, Technische Universität Dresden; Max Planck Institute for the Science of Light

  • Simon Alberti

    Max Planck Institute of Molecular Cell Biology and Genetics; Biotechnology Center, Technische Universität Dresden

  • Jan Brugués

    Max Planck Institute of Molecular Cell Biology and Genetics; Max Planck Institute for the Physics of Complex Systems; Center for Systems Biology Dresden

  • Anthony Hyman

    Max Planck Institute for Cell Biology and Genetics, Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Institute for Molecular Cell Biology and Genetics

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