Fabrication of CFO@C Core/Shell Nanoparticles by Pulsed Laser Ablation

A considerable research work is going on worldwide among the therapeutic scientific communities to use magnetic nanoparticles (NPs) for drug delivery system. Challenges to use those NPs for such in vivo applications successfully, are- biocompatibility and functionality of those NPs and control over the complex drug release system. In this project, we synthesized carbon coated cobalt ferrite (CFO) core shell nanoparticles (CSNPS) by ablating a solution of toluene and cobalt ferrite NPs with varying number of pulsed laser shots. The structure of the CSNPs was further investigated through X-ray diffraction, UV-VIS, Raman spectra and also with the high-resolution transmission electron microscopy (TEM). The XRD analysis shows that the inner structure of CFO is intact after the laser shots. Raman spectra confirms that with increasing laser shots the G band peak for Carbon becomes more prominent which infers to the crystallinity of carbon. Preliminary TEM line scan data concludes that laser ablation technique is quite efficient to manufacture carbon coated magnetic metal oxide CSNPs.