Molecular motor powered nanotransportation guided by carbon nanotubes.

ORAL

Abstract

Due to a decrease in the channel size of nanodevices, pressure-driven transport is increasingly limited by the fluid viscosity. This can be overcome by utilizing the motor protein kinesin that can walk processively along the microtubule filaments for active transport. However, using the kinesin-based transport system requires the ability to control the location and orientation of microtubules. We introduce functionalized multi-wall carbon nanotube (MWNT) tracks, aligned by dielectrophoresis, to guide kinesin powered microtubule shuttles. In order to resist shear flow and the force exerted by an electric field, the MWNT are attached to the surface via a biotin/streptavidin link. The configuration of the aligned MWNT is investigated using scanning electron microscopy and the guiding performance of the MWNT tracks is studied using fluorescence microscopy.

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Authors

  • A. Sikora

    WPI-AIMR, Tohoku University, Japan

  • J. Ramon-Azcon

    WPI-AIMR, Tohoku University, Japan

  • K. Kim

    WPI-AIMR, Tohoku University, Japan

  • K. Reaves

    Materials Science and Engineering, Texas A\&M University, Depts of Materials Science and Engineering, Physics and Astronomy, Texas A\&M University; WPI-AIMR, Tohoku University, Japan

  • H. Nakazawa

    Department of Biomolecular Engineering, Tohoku University, Japan

  • M. Umetsu

    Department of Biomolecular Engineering, Tohoku University, Japan

  • I. Kumagai

    Department of Biomolecular Engineering, Tohoku University, Japan

  • T. Adschiri

    WPI-AIMR, Tohoku University, Japan

  • H. Shiku

    WPI-AIMR, Tohoku University, Japan

  • T. Matsue

    WPI-AIMR, Tohoku University, Japan

  • W. Hwang

    Materials Science and Engineering; Department of Biomedical Engineering, Texas A\&M University

  • W. Teizer

    WPI-AIMR, Tohoku University, Japan; Department of Physics and Astronomy/Materials Science and Engineering, Texas A\&M University