Evolutionary Game Theory Analysis of Tumor Progression

POSTER

Abstract

Evolutionary game theory applied to two interacting cell populations can yield quantitative prediction of the future densities of the two cell populations based on the initial interaction terms. We will discuss how in a complex ecology that evolutionary game theory successfully predicts the future densities of strains of stromal and cancer cells (multiple myeloma), and discuss the possible clinical use of such analysis for predicting cancer progression.

Authors

  • Amy Wu

    Princeton University

  • David Liao

    University of California San Francisco

  • James Sturm

    Princeton University

  • Robert Austin

    Princeton University