The Physics Of Cell Crawling In Elastic Media

ORAL

Abstract

Understanding the motion of cells through deformable media, such as the extra-cellular matrix (ECM), is important for understanding many biological processes, such as cancer metastasis, wound healing, and organismal development. We propose a model to understand the cells' movements through ECM, described by an elastic medium. The deformations and the stress tensor are then calculated for different values of Young's modulus and Poisson's ratio. The results are then compared to the values measured experimentally.

Authors

  • Elnaz Baum-Snow

    University of Connecticut, Health Center

  • Charles Wolgemuth

    University of Connecticut, Health Center