Polymer translocation induced by bad solvent

POSTER

Abstract

We report Langevin dynamics simulation studies of a translocating homopolymer through a nano pore induced by different existing solvent conditions at the \textit{cis} and \textit{trans} compartments of the pore. Specifically, we study the mean first passage time $\langle \tau \rangle $ as a function of the chain length $N$ and determine the scaling exponent $\langle \tau \rangle \sim N^\alpha $. We also look at the mean force experienced by the chain and its conformations as a function of the translocated segments. Our studies also reveal detail picture of the translocation process which may provide insights relevant for the entry of a DNA into a host cell.

Authors

  • Christopher Lorscher

    University of Central Florida

  • Aniket Bhattacharya

    University of Central Florida

  • Tapio Ala-Nissila

    Helsinki University of Technology, TKK, Finland