Diffusion and microrheology of dense liposome suspensions

POSTER

Abstract

Phospholipid vesicles can be stabilized against fusion, up to volume fraction around 80{\%}, which is accomplished by studding the outer leaflet with charged nm-sized particles. The diffusion of such soft, flexible and hollow objects is revealed by single-particle tracking. Image analysis of time trajectories, obtained using epifluorescence imaging, was performed at sub-pixel resolution. This poster will reveal aspects of curiously heterogeneous dynamics and also quantification of microrheology in this system. Taken together, this system of charged, polydisperse, flexible objects displays rich dynamics that contrasts acutely with known behavior for hard-sphere dense particle systems.

Authors

  • Yan Yu

    Dept of Materials Science \& Engineering, University of Illinois at Urbana-Champaign, University of Illinois, Dept of Materials Science \& Engineering, Univ of Illinois at Urbana-Champaign

  • Stephen Anthony

    Department of Chemistry, University of Illinois, Chemistry, UIUC, Dept of Chemistry, University of Illinois at Urbana-Champaign, University of Illinois, Dept of Chemistry, Univ of Illinois at Urbana-Champaign

  • Sung Chul Bae

    University of Illinois, Urbana-Champaign, Dept of Materials Science \& Engineering, University of Illinois at Urbana-Champaign, University of Illinois at Urbana-Champaign, University of Illinois, Dept of Materials Science \& Engineering, Univ of Illinois at Urbana-Champaign

  • Steve Granick

    Department of Materials Science and Engineering, University of Illinois, University of Illinois, Urbana-Champaign, material science and engineering, UIUC, Materials Science and Engineering, University of Illinois, Dept of Materials Science \& Engineering, University of Illinois at Urbana-Champaign, Dept. Materials Science and Engineering, University of Illinois at Urbana-Champaign, University of Illinois at Urbana-Champaign, University of Illinois, Dept of Materials Science \& Engineering, Univ of Illinois at Urbana-Champaign, Material Science and Engineering, UIUC