Dynamics of Physiological Blood Flow in Non-Planar Curved Artery Models

The study of blood flow dynamics within arteries is crucial for understanding physiological functions and the development of various pathological conditions. In this research, high-fidelity simulations are used to analyze physiological flows in non-planar curved artery models using physiological flow rates under both pulsatile and steady flow conditions. Additional simulations are also conducted for planar models for comparison. The results are validated against available experimental data. The findings reveal that the combined effects of bending and curvature significantly impact the flow pattern, as well as the formation and evolution of vortical structures generated by secondary flows, for both steady flow at various Reynolds numbers and pulsatile flow, particularly during the acceleration and deceleration phases of the physiological waveform. The simulations also show that non-planar artery geometry may potentially reduce the risk of atherosclerosis by affecting wall shear stress distribution along the arterial wall.