Hydrodynamics of a Multicomponent Vesicle Under Strong Confinement

The biophysical lipid bilayer membrane (such as a vesicle) often consists of multiple species of macromolecules such as cholesterol, surface proteins, surfactants, and different lipids. The presence of the multiple components results in different mechanical responses, such as the bending stiffness, and this affects the vesicle's hydrodynamics. I will demonstrate some of these differences by considering multicomponent vesicles subjected to strong confinement. Comparisons will be made with single component vesicles.