Flow-Induced Deformation of Cells During Small Opening Traversal

We performed experimental and computational study of cells in microfluidic devices measuring cell traversal through the series of openings of various sizes. MCF-10A, MCF-7 and MDA-MB-231 cells were used in experiments and corresponding computational models were developed using particle-based approach. Deformability of cells under the flow conditions will be discussed. This work was done in collaboration with the group of Chwee Teck Lim from National University of Singapore.