Self-assembly and Hydrodynamics of Coarse-Grained Amphiphilic Lipids

In macroscopic models, the well-known Helfrich Hamiltonian membrane model has been extensively used to capture macroscopic physical properties of a lipid bilayer membrane. However, some phenomena such as membrane fusion and micelle formation are challenging to be described using a macroscopic framework. Therefore, in order to include the salient molecular details in a coarse-grained manner, we study the dynamics of immersed lipid bilayer membrane using Janus-type particle configurations to represent collections of amphiphilic lipids. The main idea is to solve an action field due to the hydrophobic tail-tail interactions and to obtain the domain variation of the system. From this approach, we also examine the amphiphilic lipid dynamics by forming force and torque in terms of integral formulations. We adopt an integral formulation for the numerical simulations to efficiently investigate the particle self-assembly and hydrodynamics. We will present the collecting behavior for large system and simulations of lipid bilayer membranes in a viscous fluid in this talk.