\textit{In Vivo} $\mu $PIV Measurements of Blood Flow in Small Vessels of a Rat Model.

ORAL

Abstract

Ongoing research at the University of Wisconsin Medical School is addressing the effects of perfusion of glottal tissue on voice production. Building on the approach developed by Gharib's group at CalTech for embryonic zebra fish, we have modified $\mu $PIV to measure flow in capillaries and small blood vessels in a live rat model. In lieu of seeding particles, the DPIV correlation algorithm tracks the motion of red blood cells moving through these vessels. The methodology will be presented along with a video sequence showing measurements made from muscle tissue laid nominally flat on a microscope stage. Challenges of measurements in three-dimensional geometries, $i.e.$ the throat, will be discussed.

Authors

  • Timothy Wei

    Rensselaer Polytechnic Institute

  • Nadine Conner

    Univ. of Wisconsin Medical School

  • John Russell

    Univ. of Wisconsin Medical School

  • Paul Legac

    Rensselaer Polytechnic Institute