Analysis of the reaction advection diffusion system for DNA hybridization in a microchannel

We consider the hybridization of short strand DNA in microchannels and model it as a reaction advection diffusion system in an extended space consisting of spatial dimensions as well as orientation. The model can be used to optimize the hybridization rate. We demonstrate with a shear superposition micromixer that it is possible to achieve chaotic mixing in space while simultaneously aligning the strands, thus increasing the rate of creation of double strand DNA.