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Two-Dimension Modular Scalable Electronics Biosensors

POSTER

Abstract

In this research paper, we conducted a study to evaluate how well a chip sensor responds to concentrations of COVID/FLU B antigens. We examined the chip's ability to detect and measure these target antigens by analyzing changes in resistance. To assess the chips' performance and sensitivity, we tested concentrations ranging from 0 to 100 ng/mL of the COVID and FLU antigen mixture. Additionally, we introduced 2.5 mg/mL of bovine serum albumin (BSA) as an interference protein to assess the selectivity of the sensor. By establishing a baseline resistance and comparing it with the normalized resistance, we gained insights into the chip's potential for diagnostic testing of infectious diseases.

Publication: [1] Muratore, C. et al. 2022. Laser‐Fabricated 2D Molybdenum Disulfide Electronic Sensor Arrays for Rapid, Low‐Cost, Ultrasensitive Detection of Influenza A and SARS‐Cov‐2. Advanced Materials Interfaces. 9, 18 (Mar. 2022), 2102209. DOI: https://doi.org/10.1002/admi.202102209. <br>[2] Muratore, C. and Muratore, M.K. 2020. Beyond the point of care diagnostics: Low-dimensional nanomaterials for electronic virus sensing. Journal of Vacuum Science & Technology. 38, 5 (Aug. 2020). DOI: https://doi.org/10.1116/6.0000368. <br><br>[3] Prinzi, A. (2020, August 29). How the SARS-CoV-2 EUA Antigen Tests Work | ASM.org. ASM.org. https://asm.org/Articles/2020/August/How-the-SARS-CoV-2-EUA-Antigen-Tests-Work<br>[4] Anthes, E. 2022. How accurate are At-Home Covid tests? Here's a quick guide. The New York Times.

Presenters

  • Andrea Diaz

    St. Mary's University

Authors

  • Andrea Diaz

    St. Mary's University

  • Christopher Muratore

    University of Dayton