How can Surface-Enhanced Raman Spectroscopy and nanotechnology revolutionize early cancer detection?

Surface-enhanced Raman Spectroscopy (SERS) combined with silver nanowires offers a powerful approach for early cancer detection by leveraging nanoscale physics. Silver nanowires, with their high aspect ratio and strong localized surface plasmon resonance (LSPR), significantly amplify Raman signals, enabling the detection of biomarkers at ultra-low concentrations. Sialic acid, commonly overexpressed on cancer cells, serves as a key biomarker in this context. By functionalizing silver nanowires to bind sialic acid, the system provides a distinct Raman fingerprint, allowing for early identification of cancer. This poster discusses the LSPR-induced electromagnetic enhancement in silver nanowires and its application in the sensitive detection of sialic acid, highlighting the potential of this nanotechnology-driven platform to revolutionize cancer diagnostics.