HemoClear\texttrademark: A Thin Fluid Film Device (TFFD\texttrademark ) and Model to Eliminate both Fogging and Blood on Surgical Lenses

In closed body cavity surgery, blood and water condensation can obstruct surgeons' view through scopes lenses. This forces surgeons to repeatedly remove scopes to wipe lenses during surgery, and increases surgery duration, infection risk and scarring by 10- 40{\%}. HemoClear\texttrademark , a Thin Fluid Film Device (TFFD\texttrademark ), is a layered emulsion combining VitreOx\texttrademark and fibrinogen. [1,2] VitreOx\texttrademark is an anti-fog TFFD\texttrademark , free of optical aberration, optically transparent, and super-hydrophilic, stable for up to 48 hours in closed body-cavity surgery. We find that fibrinogen can evacuated blood without interfering with anti-fog properties VitreOx\texttrademark via he hemo-affinity of fibrinogen and ~hydro-affinity of VitreOx\texttrademark . The mixing and layering of the components of HemoClear\texttrademark are tested via~\textit{in vitro}~clinical trials to optimize our TFFD\texttrademark with the smallest effective dose of fibrinogen. ~A model for 2-D versus 3-D condensation and hemo-affinity will be discussed. ~ [1]~N. Herbots, et al. ~Prov. Pat. filed 11/10/09, 11/3/11 [2] N. Herbots, et al. PCT/US12/62196 Internat. Pat. filed ~11/10/10, 10/26/12